Indazole derivatives for use in the treatment of influenza virus infection
The present invention is directed to compounds for use in the treatment or prevention of influenza virus infection.
1. A method of ameliorating symptoms of influenza virus infection comprising administering a safe and effective amount of the compound N-[5-[4-(5-{[(2R,6S)-2,6-dimethyl-4-morpholinyl]methyl}-1,3-oxazol-2-yl)-1H-indazol-6-yl]-2-(methyloxy)-3-pyridinyl]methanesulfonamide;
or a pharmaceutically acceptable salt thereof.
2. A method of ameliorating symptoms of influenza virus infection comprising administering a safe and effective amount of the compound 6-(1H-indol-4-yl)-4-(5-{[4-(1-methylethyl)-1-piperazinyl]methyl}-1,3-oxazol-2-yl)-1H-indazole;
or a pharmaceutically acceptable salt thereof.
3. A method of ameliorating symptoms of influenza virus infection comprising administering a safe and effective amount of the compound 6-(1H-indol-4-yl)-4-(5-{[4-(1-methylethyl)-1-piperazinyl]methyl}-1,3-oxazol-2-yl)-1H-indazole hemi succinate.