IP Library Granted Patent US 9,326,987
Granted Patent B2
US 9,326,987 · App. 13/821,594 · Granted May 3, 2016

Indazole derivatives for use in the treatment of influenza virus infection

Inventors: Julie Nicole Hamblin (Stevenage, GB); Paul Spencer Jones (Stevenage, GB); Suzanne Elaine Keeling (Stevenage, GB); Joelle Le (Stevenage, GB); Charlotte Jane Mitchell (Stevenage, GB); Nigel James Parr (Stevenage, GB)
Assignee: Glaxo Group Limited
A61K31/5377A61K31/416A61K31/422A61K31/427A61K31/4245A61K31/437A61K31/4439A61K31/454A61K31/496A61K31/5386C07D413/14
View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 9,326,987
App. No.
13/821,594
Granted
May 3, 2016
Kind
B2
Abstract

The present invention is directed to compounds for use in the treatment or prevention of influenza virus infection.

Claims (5)

1. A method of ameliorating symptoms of influenza virus infection comprising administering a safe and effective amount of the compound N-[5-[4-(5-{[(2R,6S)-2,6-dimethyl-4-morpholinyl]methyl}-1,3-oxazol-2-yl)-1H-indazol-6-yl]-2-(methyloxy)-3-pyridinyl]methanesulfonamide;

or a pharmaceutically acceptable salt thereof.

2. A method of ameliorating symptoms of influenza virus infection comprising administering a safe and effective amount of the compound 6-(1H-indol-4-yl)-4-(5-{[4-(1-methylethyl)-1-piperazinyl]methyl}-1,3-oxazol-2-yl)-1H-indazole;

or a pharmaceutically acceptable salt thereof.

3. A method of ameliorating symptoms of influenza virus infection comprising administering a safe and effective amount of the compound 6-(1H-indol-4-yl)-4-(5-{[4-(1-methylethyl)-1-piperazinyl]methyl}-1,3-oxazol-2-yl)-1H-indazole hemi succinate.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 31, 2014
From: GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED
To: GLAXO GROUP LIMITED
Reel/Frame 033452/0594 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 24, 2013
From: BALDWIN, IAN ROBERT; DOWN, KENNETH DAVID; FAULDER, PAUL; GAINES, SIMON; HAMBLIN, JULIE NICOLE; HARRISON, ZOE ALICIA; JONES, KATHERINE LOUISE; JONES, PAUL SPENCER; KEELING, SUZANNE ELAINE; LE, JOELLE; LUNNISS, CHRISTOPHER JAMES; MITCHELL, CHARLOTTE JANE; PARR, NIGEL JAMES; RITCHIE, TIMOTHY JOHN; ROBINSON, JOHN EDWARD; SIMPSON, JULIET KAY; SMETHURST, CHRISTIAN ALAN PAUL; WASHIO, YOSHIAKI
To: GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED
Reel/Frame 031467/0771 →
Continuity (2)
Provisional Application 61380752 · Sep 8, 2010
Related Publication 20130165433A1 · Jun 27, 2013