FGFR-Fc fusion proteins and the use thereof
The present invention belongs to the field of biotechnology and relates to the treatment of diseases, especially the treatment of FGF overexpression-related diseases. Particularly, the present invention relates to FGFR-Fc fusion proteins and the use thereof in the treatment of angiogenesis regulation-related diseases. More particularly, the present invention relates to isolated soluble FGFR-Fc fusion proteins and their applications in manufacture of the medicament for the treatment of angiogenesis regulation-related diseases.
1. An isolated soluble fusion protein comprising SEQ ID NO: 12.
2. An isolated soluble fusion protein comprising SEQ ID NO: 13.
3. An isolated soluble fusion protein comprising SEQ ID NO: 14.
4. The isolated soluble fusion protein, according to claim 1 , which consists of SEQ. ID NO:12.
5. The isolated soluble fusion protein, according to claim 2 , which consists of SEQ. ID NO:13.
6. The isolated soluble fusion protein, according to claim 3 , which consists of SEQ. ID NO:14.