IP Library Granted Patent US 10,217,540
Granted Patent B2
US 10,217,540 · App. 13/852,091 · Granted Feb 26, 2019

Multifunctional nanoparticles

Inventors: Ou Chen (Somerville, MA); Moungi G. Bawendi (Cambridge, MA)
Assignee: MASSACHUSETTS INSTITUTE OF TECHNOLOGY
H01B1/00A61K49/0093A61K49/1818G01N33/5005Y10T428/2982Y10T428/2993
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Quick Facts
Patent No.
US 10,217,540
App. No.
13/852,091
Granted
Feb 26, 2019
Kind
B2
Abstract

Multifunctional nanoparticles can include two or more different populations of nanocrystals that impart a combination of properties arising from the constituent populations in a single, multifunctional nanoparticle.

Claims (16)

1. A multifunctional nanoparticle comprising:

a first population of nanoparticles with a first property;

a second population of nanoparticles with a second property, wherein the second property is different from the first property, the first population of nanoparticles and the second population of nanoparticles having a photoluminescence at different desired wavelengths; and

an assembly polymer associated with the first population of nanoparticles and the second polymer of the nanoparticles,

wherein the first population of nanoparticles and the second population of nanoparticles are substantially evenly distributed and impart a combination of properties arising from the first and second populations in a single multifunctional nanoparticle.

2. The multifunctional nanoparticle of any one of claim 1 , wherein the multifunctional nanoparticle has a diameter no greater than 1,000 nm.

3. The multifunctional nanoparticle of any one of claim 1 , wherein the multifunctional nanoparticle has a diameter no greater than 500 nm.

4. The multifunctional nanoparticle of any one of claim 1 , wherein the multifunctional nanoparticle has a diameter no greater than 100 nm.

5. The multifunctional nanoparticle of any one of claim 1 , wherein the first population has an average diameter no greater than 50 nm, and the second population has an average diameter no greater than 50 nm.

6. The multifunctional nanoparticle of any one of claim 1 , wherein the assembly polymer is non-covalently associated with the first and second populations.

7. The multifunctional nanoparticle of any one of claim 1 , further comprising a shell including a silicon oxide on a surface of the multifunctional nanoparticle.

8. The multifunctional nanoparticle of claim 7 , wherein the shell including a silicon oxide is further functionalized.

9. The multifunctional nanoparticle of claim 8 , wherein the shell including a silicon oxide is further functionalized with a dye, a polymer, a biomolecule, or a member of a binding pair.

10. The multifunctional nanoparticle of any one of claim 1 , wherein the first population is a population of semiconductor nanocrystals.

11. The multifunctional nanoparticle of any one of claim 1 , wherein the second population is a population of semiconductor nanocrystals, magnetic nanoparticles, metal nanoparticles, carbon-based nanoparticles, polymer nanoparticles, or ceramic nanoparticles.

12. The multifunctional nanoparticle of any one of claim 1 , wherein the first population is a population of semiconductor nanocrystals and the second population is a population of semiconductor nanocrystals or a population of magnetic nanoparticles.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 25, 2013
From: CHEN, OU; BAWENDI, MOUNGI G.
To: MASSACHUSETTS INSTITUTE OF TECHNOLOGY
Reel/Frame 030677/0504 →
CONFIRMATORY LICENSE Recorded May 31, 2013
From: MASSACHUSETTS INSTITUTE OF TECHNOLOGY
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 030519/0894 →
Continuity (2)
Provisional Application 61616663 · Mar 28, 2012
Related Publication 20130259808A1 · Oct 3, 2013