Antimicrobially active compositions based on zinc compound, glycerine monoalkyl ether and antioxidant

1. Antimicrobial composition in the form of a concentrate, the active ingredients of the composition consisting of:

(i) 0.1 to 50 wt. % of at least one zinc compound selected from zinc salt and zinc oxide, where the quantity of zinc compound is stated as anhydrous zinc oxide;

(ii) 10 to 90 wt. % of at least one glycerine monoalkyl ether of the general formula R—O—CH 2 —CHOH—CH 2 OH,

wherein R is a branched or unbranched C 1 -C 24 alkyl group, wherein the alkyl group can be substituted with one or more hydroxy and/or C 1 -C 4 alkoxy group(s) and/or the alkyl chain can be interrupted by up to four oxygen atoms; and

(iii) 10 −4 to 0.9 wt. % of at least one antioxidant;

and optionally

(iv) one or more alkanediols.

2. The composition according to claim 1 , further comprising (iv) one or more alkanediols.

3. The composition according to claim 1 , wherein the zinc compound is selected from the group consisting of zinc oxide, zinc chloride, zinc sulphate, zinc phosphate, zinc carbonate, zinc pyrithione, zinc ascorbate, zinc dehydracetate, zinc carboxylate, zinc lactate, zinc citrate, zinc stearate, zinc hydroxystearate, zinc benzoate, zinc sorbate, zinc salicylate, zinc gluconate, zinc ricinoleate, zinc undecylenate GP and zinc pyrrolidone-carboxylate.

4. The composition according to claim 1 , wherein R possesses 3 to 20 carbon atoms.

5. The composition according to claim 1 , wherein the weight ratio (w/w) of component (i) to component (ii) is in the range of from 20:1 to 1:400, wherein the quantity of zinc compound is stated as anhydrous zinc oxide.

6. The composition according to claim 2 , wherein the alkanediol is a 1,2-alkanediol which has 2 to 18 carbon atoms.

7. The composition according to claim 2 , wherein the weight ratio (w/w) of component (i) to component (iv) is in the range of from 1:50 to 5:1, wherein the quantity of zinc compound is stated as anhydrous zinc oxide.

8. The composition according to claim 2 , wherein the weight ratio (w/w) of component (ii) to component (iv) is 10:1 to 1:10.

9. The composition according to claim 1 , wherein the antioxidant is selected from the group consisting of 3-tert-butyl-4-hydroxyanisole, 2,6-ditert-butyl-p-cresol, toco-pherol, vitamin E and derivatives thereof, p-hydroxybenzoic acid esters, dimethyloldimethylhydantoin, and N-acylamino acids and salts thereof.

10. The composition according to claim 1 , wherein the weight ratio (w/w) of component (ii) to component (iii) is at least 100:1.

11. The composition according to claim 1 ,

(i)

(ii)

(iii)

(iv) further comprising 10 to 90 wt. % of alkanediol.

12. Method for the production of the composition according to claim 1 in the form of a concentrate, comprising:

providing component (i) in solvent, and

adding component (ii), optionally in combination with component (iii), and if present component (iv), to component (i).

13. A method for the treatment of a microbially caused disease, comprising administrating to a subject in need thereof an effective amount of the antimicrobial composition according to claim 1 .

14. A method of controlling bacteria, yeasts, fungi, viruses and/or protozoa on human skin or mucous membrane, comprising administering to a subject in need thereof an effective amount of the antimicrobial composition according to claim 1 .

15. The composition according to claim 1 , wherein R is 2-ethylhexyl.

16. The composition according to claim 2 , wherein the alkanediol is 1,2-octanediol.

17. The composition according to claim 1 , wherein the antioxidant is vitamin E.

18. The composition according to claim 1 , wherein the active ingredients consist of:

(i) 2 to 30 wt. % of zinc compound, where the quantity of zinc compound is stated as anhydrous zinc oxide,

(ii) 14 to 30 wt. % of glycerine monoalkyl ether,

(iii) 0.006 to 0.02 wt. % of antioxidant, and optionally

(iv) 33 to 65 wt. % of alkanediol.