Device for performing a chemical transformation in fluidic media
A device is provided for performing chemical transformation in a fluid, with a flow distributor having at least one fluid medium inlet, at least one fluid medium outlet, and at least one confinement wherein the chemical transformation is performed; and a means for rotating, rocking, wagging, or oscillating the device. At least one confinement may be equipped with a provision for providing heat, cooling, sound, light or other types of radiation, such provision being contacted to an external source through an actuator shaft. The flow distributor may be provided with sectors connected with the centrally located fluid medium inlet and a designated peripheral, fluid medium outlet. The means for rotating, rocking, wagging, or oscillating the device may be an element producing magnetic fields or a shall mechanically connected to an external actuating device.
1. A device for performing biological or chemical transformation, or physical or chemical trapping in fluidic media comprising:
a. a hollow tubular flow distributor having at least one central fluid medium inlet, at least one peripheral fluid medium outlet, and at least one confinement wherein said transformation or trapping is performed; and
b. a means for rotating, rocking, wagging, or oscillating the device,
wherein the at least one confinement of the flow distributor houses one or more solid members that participate in or facilitate(s) a biological or chemical transformation involving at least one agent distributed with the flow, or causes said agent to become physically or chemically trapped by the one or more solid members, and
wherein the at least one confinement is in a form of two or more confinements that are connected in series and that are filled with different solid members capable of carrying out different chemical transformations.
2. The device according to claim 1 , wherein each solid member is provided in one or more cartridges or as monolithic packing, which are placed within the at least one confinement.
3. The device according to claim 2 , wherein said cartridges are replaceable.
4. The device according to claim 1 , wherein the flow distributor is made from or coated with a material that is able to catalyze at least one agent to undergo a chemical reaction.
5. The device according to claim 1 , wherein the means for rotating, rocking, wagging, or oscillating the device is an element producing magnetic fields.
6. The device according to claim 1 , wherein the means for rotating, rocking, wagging, or oscillating the device is a solid or hollow shaft mechanically connected to an external actuating device.
7. The device according to claim 1 , wherein the confinement contains a solid member selected from the group consisting of:
a. a catalyst;
b. a solid phase containing a physically trapped or chemically bonded reagent capable of entering a chemical reaction with an agent transported by the fluidic flow;
c. an immobilized biological entity capable of transforming agents supplied by the fluidic flow;
d. a support material suitable for carrying out solid phase synthesis;
e. a solid sorbent capable of trapping matter from the fluidic flow; and
f. a stationary phase suitable for chromatographic separation.
8. A method of performing biological or chemical transformation, or physical or chemical trapping in fluidic media comprising:
a. providing the device of claim 1 ; and
b. creating a convective flow of fluidic medium through the device by rotating, rocking, wagging, or oscillating the device.
9. The device according to claim 1 , wherein the flow distributor is coated with a material that is capable of chemically transforming at least one agent introduced to a flow channel of the flow distributor.
10. A device for performing biological or chemical transformation, or physical or chemical trapping in fluidic media comprising:
a. a hollow tubular flow distributor having at least one central fluid medium inlet, at least one peripheral fluid medium outlet, and at least one confinement wherein said transformation or trapping is performed; and
b. a means for rotating, rocking, wagging, or oscillating the device,
wherein the at least one confinement of the flow distributor houses one or more solid members that participate in or facilitate(s) a biological or chemical transformation involving at least one agent distributed with the flow, or causes said agent to become physically or chemically trapped by the one or more solid members, and
wherein the at least one confinement is in a form of two or more confinements that are connected in parallel and that are filled with different solid members capable of carrying out different chemical transformations.
11. The device according to claim 10 , further comprising,
a combination of confinements connected in series and parallel.