Abnormal intraocular pressure treatment
Methods and compositions for reducing intraocular pressure in a patient, particularly a human patient, are described. In particular, compositions are disclosed that contain an anthocyanoside or an extract comprising it, a proanthhocyanidin or an extract comprising it and combinations thereof. The compositions are useful for lowering intraocular pressure.
1. A pharmaceutical composition for the treatment of high or abnormal intraocular pressure comprising (1) about 160 milligrams of at least one Vaccinium myrtillus extract per day, (2) about 80 milligrams of at least one pine bark extract per day, and (3) a pharmaceutically acceptable excipient.
2. The composition of claim 1 , wherein said pine bark extract is from a pine of the Pinus pinaster species.
3. The composition of claim 1 , for the treatment of ocular hypertension wherein said ocular hypertension comprises the following symptoms:
(a) an intraocular pressure greater than 21 mm Hg in one or both eyes as measured by applanation tonometry on 2 or more occasions;
(b) an absence of glaucomatous defects on visual field testing;
(c) normal appearance of the optic disc and nerve fiber layer; and
(d) open angles on gonioscopy, with no history of angle closure.
4. The composition of claim 1 , wherein said composition is orally administered.