Phenyl amino pyrimidine compounds and uses thereof

Inventors: Christopher John Burns (Richmond, AU); Andrew Donohue (Richmond, AU); John Thomas Feutrill (Richmond, AU); Thao Lien Thi Nguyen (Richmond, AU); Andrew Frederick Wilks (Richmond, AU); Jun Zeng (Richmond, AU)

Assignee: YM Biosicences Australia PTY LTD

C07D239/42 C07D295/02 C07D295/12 C07D401/12 C07D401/14 C07D403/12 C07D405/12 C07D417/12

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Quick Facts

Patent No.: US 9,238,628
App. No.: 13/913,362
Granted: Jan 19, 2016
Kind: B2

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Abstract

The present invention relates to phenyl amino pyrimidine compounds which are inhibitors of protein kinases including JAK kinases. In particular the compounds are selective for JAK2 kinases. The kinase inhibitors can be used in the treatment of kinase associated diseases such as immunological and inflammatory diseases including organ transplants; hyperproliferative diseases including cancer and myeloproliferative diseases; viral diseases; metabolic diseases; and vascular diseases.

Claims (3)

1. A compound having the structure of:

or a pharmaceutically acceptable salt thereof.

2. A compound having the structure of:

Assignments (5)

ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 7, 2023

From: SIERRA ONCOLOGY LLC

To: GLAXOSMITHKLINE LLC

Reel/Frame 063879/0821 →

CHANGE OF NAME Recorded May 26, 2023

From: SIERRA ONCOLOGY, INC.

To: SIERRA ONCOLOGY LLC