Method for enhancing PPARγ expression
The present invention provides a method for enhancing PPARγ expression, comprising administering a subject in need thereof an effective amount of Lactobacillus gasseri PM-A0005, which was deposited under Budapest Treaty in the China Center for Type Culture Collection (CCTCC), China with Deposition No. M 207039.
1. A method for enhancing peroxisome proliferator-activated receptor γ (PPARγ) expression in a subject in need thereof, comprising administering to the subject in need thereof an effective amount of Lactobacillus gasseri PM-A0005, which was deposited in the China Center for Type Culture Collection (CCTCC), China, with Deposit No. M 207039.
2. The method of claim 1 , wherein the Lactobacillus gasseri PM-A0005 is orally administered to the subject.
3. The method of claim 2 , wherein the effective amount of the Lactobacillus gasseri PM-A0005 is between 1×108 CFU/kg/day to 1×109 CFU/kg/day of the body weight of the subject.
4. The method of claim 3 , wherein the effective amount of the Lactobacillus gasseri PM-A0005 is between 5×108 CFU/kg/day to 6×108 CFU/kg/day of the body weight of the subject.
5. The method of claim 4 , wherein the effective amount of the Lactobacillus gasseri PM-A005 is about 55×108 CFU/kg/day of the body weight of the subject.
6. The method of claim 1 , wherein the he Lactobacillus gasseri PM-A0005 is in a form of a composition.
7. The method of claim 6 , wherein the composition is a pharmaceutical composition.
8. The method of claim 6 , wherein the composition is a food composition.
9. The method of claim 8 , wherein the food composition is milk, fermented milk, a drink, a sports beverage, a nutritional additive, a dietary supplement, candy, or gelatin.
10. The method of claim 1 , wherein the PPARγ expression increases in the lung of the subject.
11. The method of claim 1 , wherein the PPARγ expression increases in the lung draining lymph node of the subject.
12. The method of claim 1 , wherein the PPARγ expression increases in the gut of the subject.
13. The method of claim 12 , wherein the PPARγ expression increases in the mesenteric lymph node of the subject.