Treatment of Psychiatric Conditions
The number of acne lesions in a human subject is reduced by administering to the subject a pharmaceutical composition that includes a pharmaceutically acceptable carrier and a therapeutically effective amount of an agent that selectively binds IL-1α. Anxiety and other psychiatric conditions are also improved with this treatment.
1 - 6 . (canceled)
7 . A method of reducing anxiety in a human subject, the method comprising the step of administering to the subject a pharmaceutical composition comprising a pharmaceutically acceptable carrier and an amount of an agent that selectively binds IL-1α effective to reduce anxiety in the subject.
8 . The method of claim 7 , wherein the agent is an anti-IL-1α antibody.
9 . The method of claim 8 , wherein the anti-IL-1α antibody is a monoclonal antibody.
10 . The method of claim 8 , wherein the monoclonal antibody is an IgG1.
11 . The method of claim 8 , wherein the monoclonal antibody comprises a complementarity determining region of MABp1.
12 . The method of claim 8 , wherein the monoclonal antibody is MABp1.
13 . The method of claim 7 , wherein the subject has acne.