Absolute temperature method for disposable glucose strip
A bio-fluid test strip includes a fluid receiving area and a contact pad area for interfacing with a fluid sensing device. The test strip includes a fluid sensing electrodes and a first temperature sensing resistor in the fluid receiving area. The test strip further includes a second temperature sensing resistor in the contact pad area. The first and second temperature sensing resistors together provide an indication of the temperature difference between the fluid sensing area and ambience.
1. A fluid test strip comprising:
a fluid receiving area configured to receive a fluid to be tested;
a first electrode positioned in the fluid receiving area;
a second electrode positioned in the fluid receiving area;
an enzyme covering the first and second electrodes;
a first contact pad electrically coupled to the first electrode;
a second contact pad electrically coupled to the second electrode; and
a first resistor positioned within the fluid receiving area and configured to output a temperature signal indicative of a temperature of the fluid to be tested; and
a dielectric material between the first resistor and the enzyme.
2. The fluid test strip of claim 1 , further comprising
a second resistor electrically coupled to the first resistor at a node.
3. The fluid test strip of claim 2 wherein the temperature signal is a differential temperature signal indicative of a temperature difference between the first and the second resistors.
4. The fluid test strip of claim 3 wherein the further comprising a third contact pad electrically coupled to the first resistor.
5. The fluid test strip of claim 4 wherein the third contact pad is electrically coupled to the node.
6. The fluid test strip of claim 1 wherein the first contact pad is configured to supply a first voltage to the first electrode.
7. The fluid test strip of claim 6 wherein the second contact pad is configured to supply an output signal indicative of a concentration of a compound in the fluid to be tested.
8. The fluid test strip of claim 7 wherein the output signal is a current passing between the first and the second electrodes.
9. A device for measuring a concentration of a compound in a fluid, the device comprising:
a substrate;
a first electrode overlying the substrate;
a second electrode overlying the substrate;
a first resistor overlying the substrate;
an enzyme overlying the first electrode, the second electrode, and the first resistor, the enzyme configured to react with the compound when the fluid contacts the enzyme;
a dielectric material between the first resistor and the enzyme;
a first contact pad on the substrate, the first contact pad being configured to supply a first voltage to the first electrode;
a second contact pad on the substrate, the second contact pad being electrically coupled to the second electrode, the second contact pad configured to output a compound concentration signal indicative of the concentration of the compound in the fluid; and
a third contact pad coupled to the first resistor and configured to output a temperature signal indicative of a temperature of the fluid.
10. The device of claim 9 , further comprising a thermal connector on the substrate, the thermal connector configured to couple the first resistor to the fluid.
11. The device of claim 9 comprising:
a second resistor on the substrate, the second resistor being electrically coupled to the first resistor and the third contact pad, the second resistor being positioned outside an area of the device covered by the enzyme;
a fourth contact pad on the substrate, the fourth contact pad being electrically coupled to the second resistor; and
a fifth contact pad on the substrate, the fifth contact pad being electrically coupled to the first resistor.
12. The device of claim 11 wherein the fourth contact pad is configured to supply a second voltage to the first resistor, the fifth contact pad being configured to supply a third voltage to the second resistor, the third contact pad being electrically coupled between the first and the second resistors, the output temperature signal having a voltage between the first and second voltages and indicative of a temperature difference between the first and second resistors.
13. The device of claim 12 wherein the substrate and the contact pads are configured to interface with a compound concentration sensor configured to supply the first, second, and third voltages to the first, fourth, and fifth contact pads, and to receive the compound concentration signal and the output temperature signal from the second and third contact pads, respectively.
14. A system comprising:
a fluid test strip including:
a fluid receiving area configured to receive a fluid;
a test electrode in the fluid receiving area configured to provide an output signal indicative of a concentration of a compound in the fluid;
a dry area spaced apart from the fluid receiving area;
a first contact pad in the dry area electrically coupled to the test electrode;
a first temperature sensor having a first portion in the dry area and a second portion in the fluid receiving area;
a dielectric material between the first portion and the fluid; and
a second contact pad in the dry area and electrically coupled to the first temperature sensor, the first temperature sensor being configured to output a first temperature signal indicative of a difference in a temperature of the fluid and a temperature of the dry area;
a fluid test strip reader including:
a port configured to receive the fluid test strip; and
control circuitry configured to supply power to the fluid test strip, to receive the first temperature signal and the output signal from the fluid test strip, and to calculate a value of the concentration of the compound in the fluid based on the first temperature signal and the output signal.
15. The system of claim 14 wherein the fluid test strip reader includes a second temperature sensor configured to provide a second temperature signal to the control circuitry.
16. The system of claim 15 wherein the control circuitry calculates the value of the concentration of the compound based in part on the second temperature signal.
17. The system of claim 16 wherein the second temperature signal is indicative of an ambient temperature.
18. The system of claim 17 wherein the control circuitry calculates a temperature of the fluid based on the first and the second temperature signals.
19. A biosensor, comprising:
a fluid receiving area, including
a fluid sensor having a plurality of fluid sensor electrodes;
an enzyme covering the fluid sensor electrodes;
a fluid temperature sensor element; and
a dielectric material between the enzyme and the fluid temperature sensor element; and
a dry area, spaced apart from the fluid receiving area, the dry area including
an ambient temperature sensor element; and
a plurality of contact pads, each contact pad coupled to one of the fluid sensor electrodes or to the temperature sensor element.
20. The biosensor of claim 19 , further comprising a thermal connector in thermal communication with the fluid temperature sensor element, the thermal connector having a surface area that is substantially larger than a surface area of the fluid temperature sensor element.
21. The biosensor of claim 19 wherein the ambient temperature sensor element is coupled in parallel with the fluid temperature sensor element to provide a differential temperature measurement of the fluid relative to an ambient temperature.