Methods of Treating Depression and Other Related Diseases
The invention relates to methods for treating depression, anxiety, and other related diseases by administering a peptide NMDAR partial agonist.
1 . A method for treating dysthymic disorder in a patient in need thereof, comprising administering to said patient a pharmaceutically acceptable composition comprising:
a compound represented by:
or pharmaceutically acceptable salts, homologs, or hydrates thereof; and
an excipient.
2 . The method of claim 1 , comprising administering the composition every week or every two weeks to said patient.
3 . The method of claim 1 , wherein the composition comprises a 1 mg/kg to about 10 mg/kg dose of the compound.
4 . The method of claim 3 , wherein administration of a single dose is effective for up to 4 days.
5 . The method of claim 1 , further comprising administering another antidepressant drug.
6 . The method of claim 2 , further comprising administering another antidepressant drug.
7 . A method for treating dysthymic disorder in a patient in need thereof, comprising administering to said patient about 1 mg/kg to about 10 mg/kg of a compound represented by:
or pharmaceutically acceptable salts thereof.
8 . The method of claim 7 , wherein about 5 mg/kg of the compound is administered.