IP Library › Granted Patent US 9,238,794
Granted Patent B2
US 9,238,794 · App. 13/946,032 · Granted Jan 19, 2016

Synthetic surfaces for culturing stem cell derived oligodendrocyte progenitor cells

Inventors: Christopher Bankole Shogbon (Corning, NY); Yue Zhou (Horseheads, NY); Ralph Brandenberger (Palo Alto, CA)
Assignee: Asterias Biotherapeutics, Inc.
C12N5/0622C12N5/0068C12N2500/90C12N2506/02C12N2533/30
View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 9,238,794
App. No.
13/946,032
Granted
Jan 19, 2016
Kind
B2
Abstract

Synthetic surfaces suitable for culturing stem cell derived oligodendrocyte progenitor cells contain acrylate polymers formed from one or more acrylate monomers. The acrylate surfaces, in many cases, are suitable for culturing stem cell derived oligodendrocyte progenitor cells in chemically defined media.

Claims (8)

1. A cell culture comprising 1) an oligodendrocyte progenitor cell disposed on a polymer material, wherein the polymer material comprises an acrylate or a diacrylate; and 2) a culture medium.

2. The cell culture of claim 1 , wherein the oligodendrocyte progenitor cell is a human oligodendrocyte progenitor cell.

3. The cell culture of claim 1 , wherein the oligodendrocyte progenitor cell is derived from a human embryonic stem cell.

4. The cell culture of claim 1 , wherein the oligodendrocyte progenitor cell is derived from an induced pluripotent stem cell.

5. A cell culture comprising 1) a progenitor cell expressing Nestin and Olig1 disposed on a polymer material, wherein the polymer material comprises an acrylate or a diacrylate; and 2) a culture medium.

6. The cell culture of claim 5 , wherein the progenitor cell is a human oligodendrocyte progenitor cell.

7. The cell culture of claim 5 , wherein the progenitor cell is derived from a human embryonic stem cell.

8. The cell culture of claim 5 , wherein the progenitor cell is derived from an induced pluripotent stem cell.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 12, 2013
From: GERON CORPORATION
To: ASTERIAS BIOTHERAPEUTICS, INC.
Reel/Frame 031620/0567 →
Continuity (3)
Continuation 12362250 · Jan 29, 2009
Provisional Application 61063010 · Jan 30, 2008
Related Publication 20140134729A1 · May 15, 2014