Methods And Compositions For Administering A Specific Wavelength Phototherapy
Methods are disclosed for administering electromagnetic radiation (EMR), which may include filtering EMR from part of the EMR spectrum while allowing passage of EMR at a desired wavelength. A fluorescent component may be included, which absorbs EMR at one wavelength and emits EMR at the desired wavelength. Uses may include the treatment of acne. Pruritus may also be treated by allowing the passage to the skin of a particular UV wavelength from sunlight, which has an immunosuppressive effect, while protecting the skin from other harmful UV radiation.
1 . A method of delivering, from a light source that emits a broad spectrum of electromagnetic radiation (EMR) including a predetermined wavelength band, a dose of EMR within the predetermined wavelength band to an object, wherein the object is covered with a covering composition that selectively allows passage of EMR within the predetermined wavelength band, comprising the steps of:
providing between the light source and the object a fluorescent component that emits EMR within the predetermined wavelength band after absorbing at a shorter wavelength within the broad spectrum emitting from the light source; and
exposing the fluorescent component and the object to the light source, whereby the object is exposed to EMR from the light source within the predetermined wavelength band, and EMR emitted by the fluorescent component.
2 . The method of claim 1 , wherein the fluorescent component is part of the covering composition.
3 . The method of claim 2 , wherein the covering composition selectively allows passage of EMR at the shorter wavelength in addition to the predetermined wavelength band.
4 . The method of claim 1 , wherein the covering composition is part of a first layer of material, and the fluorescent component is part of a second layer on top of the first layer of material.
5 . The method of claim 4 , wherein the first layer is a cream or powder, and the second layer is a liquid, wherein said step of providing comprises spraying the liquid on the first layer.
6 . The method of claim 1 , wherein the object is the skin of a human subject, and wherein the covering composition is a topical cream or powder that blocks at least a portion of the ultraviolet light spectrum.
7 . The method of claim 6 , wherein said portion of the ultraviolet light spectrum comprises the UVA spectrum (about 320 nm to about 400 nm).
8 . The method of claim 7 , wherein said portion of the ultraviolet light spectrum comprises the UVA and UVB spectra (about 290 nm to about 400 nm).
9 . The method of claim 6 , wherein the human subject suffers from acne, and wherein the amount of light at the predetermined wavelength band is an effective amount for treatment of the acne.
10 . The method of claim 9 , wherein the predetermined wavelength band includes a range of wavelengths that include wavelengths within the range of about 405 nm to about 470 nm.
11 . The method of claim 1 , wherein the fluorescent component is 7-diethylamino-4-methylcoumarin (CAS #91-44-1).
12 . A kit comprising:
a broad-spectrum sunscreen with a sun protection factor (SPF) of at least 15;
a topical cream or spray, suitable for application to human skin, comprising a fluorescent component that emits EMR within a predetermined wavelength band after absorbing at a shorter wavelength within the broad spectrum of sunshine, wherein the sunscreen allows passage of EMR at the predetermined wavelength.
13 . A method for treating a human subject with chronic or acute pruritus by delivering a dose of ultraviolet radiation to affected skin of the subject, comprising the steps of:
covering the affected skin with a topical composition which selectively allows passage of one predetermined band of EMR within the UVA or UVB range (about 290 nm to about 400 nm), while excluding EMR of wavelengths shorter than said band; and
exposing the affected skin to solar radiation until the affected skin has received a dose of EMR within the predetermined band effective to induce immunosuppression in the skin of the subject.
14 . The method of claim 13 , wherein the topical composition also excludes EMR at wavelengths longer than the predetermined band.
15 . The method of claim 14 , wherein the predetermined band is within the UVB range (about 290 nm to about 320 nm).
16 . The method of claim 15 , wherein the predetermined band is a narrow band at about 311 nm, and the dose of EMR is the range of about 10 to about 30 mJ/cm 2 .
17 . The method of claim 14 , wherein the predetermined band is within the UVA range (about 320 nm to about 400 nm).