Method to prevent cancer metastasis to bone
A method for treating osteoporosis and related methods are disclosed. The methods generally comprise administering to a patient in need of treatment an effective amount of tris(8-quinolinolato)gallium(III) or an analog thereof.
1. A method for preventing, or delaying the onset of, bone metastasis of cancer in a patient, comprising identifying a patient diagnosed with lung cancer, breast cancer, prostate cancer, lymphoma or multiple myeloma, but without bone metastasis, and administering to said patient an effective amount of a compound of Formula (I) or a pharmaceutically acceptable salt thereof
wherein R 1 represents hydrogen, a halogen or a sulfono group SO 3 M, in which M is a metal ion, and R 2 represents hydrogen, or R 1 is Cl and R 2 is I, thereby preventing, or delaying the onset of, bone metastasis in said patient.
2. The method of claim 1 wherein R 1 and R 2 are H.