Sustained release beads and suspensions including the same for sustained delivery of active ingredients
Sustained-released beads providing active ingredients over an extended period of time to an individual orally ingesting the sustained release beads. The sustained-release beads can be part of a suspension wherein the sustained-release beads are suspended and evenly dispersed in the suspension. Binding agents are used to form the structural framework of the sustained released beads and retain the active ingredients without chemical or electrical bonding. The components of the dispersion medium are GRAS designated, making the suspension suitable for use as a food product.
1. Packetized sustained-release beads comprising:
a packet;
a selected quantity of sustained-release beads contained in the packet, each of the sustained-release beads consisting of:
40 wt % to 95 wt % of one or more binding agents;
5 wt % to 60 wt % of active ingredients consisting of one or more of stimulants, electrolytes, vitamins, and minerals; and
up to 4.32 wt % of water;
wherein the one or more binding agents and the one or more active ingredients are mixed together throughout each sustained-release bead.
2. The packetized sustained-release beads as claimed in claim 1 , wherein the binding agents are selected from the group consisting of methyl cellulose, ethyl cellulose, microcrystalline cellulose, croscarmellose sodium, dicalcium phosphate, cellulose, hypromellose, hydroxypropyl methylcellulose, carboxymethylcellulose, and hydroxyethyl cellulose.
3. The packetized sustained-release beads of claim 1 , wherein the sustained-release beads include only ingredients that are GRAS-compliant or present in GRAS-compliant quantities.
4. The packetized sustained-release beads of claim 1 , wherein the selected quantity of sustained-release beads includes first sustained-release beads and second sustained-release beads and wherein the composition of active ingredients in the first sustained-release beads is different from the composition of active ingredients in the second sustained-release beads.
5. The packetized sustained-release beads of claim 1 , wherein the selected quantity of sustained-release beads includes first sustained-release beads and second sustained-release beads and wherein the first sustained-release beads release the at least one or more active ingredients contained therein at a rate different from the rate at which the second sustained-release beads release the one or more active ingredients contained therein.
6. The packetized sustained-release beads of claim 1 , wherein the selected quantity of sustained-release beads includes first sustained-release beads and second sustained-release beads;
wherein the composition of active ingredients in the first sustained-release beads is different from the composition of active ingredients in the second sustained-release beads; and
wherein the first sustained-release beads release the at least one or more active ingredients contained therein at a rate different from the rate at which the second sustained-release beads release the one or more active ingredients contained therein.
7. Packetized sustained-release beads comprising:
a packet;
a selected quantity of sustained-release beads contained in the packet, each of the sustained-release beads consisting of:
40 wt % to 95 wt % of one or more binding agents;
5 wt % to 60 wt % of active ingredients consisting of one or both of vitamins and electrolytes, or both; and
up to 4.32 wt % of water;
wherein the one or more binding agents and the one or more active ingredients are mixed together throughout each sustained-release bead.
8. The packetized sustained-release beads as claimed in claim 7 , wherein the binding agents are selected from the group consisting of methyl cellulose, ethyl cellulose, microcrystalline cellulose, croscarmellose sodium, dicalcium phosphate, cellulose, hypromellose, hydroxypropyl methylcellulose, carboxymethylcellulose, and hydroxyethyl cellulose.
9. The packetized sustained-release beads of claim 7 , wherein the sustained-release beads include only ingredients that are GRAS-compliant or present in GRAS-compliant quantities.
10. The packetized sustained-release beads of claim 7 , wherein the selected quantity of sustained-release beads includes first sustained-release beads and second sustained-release beads and wherein the composition of active ingredients in the first sustained-release beads is different from the composition of active ingredients in the second sustained-release beads.
11. The packetized sustained-release beads of claim 7 , wherein the selected quantity of sustained-release beads includes first sustained-release beads and second sustained-release beads and wherein the first sustained-release beads release the at least one or more active ingredients contained therein at a rate different from the rate at which the second sustained-release beads release the one or more active ingredients contained therein.
12. The packetized sustained-release beads of claim 7 , wherein the selected quantity of sustained-release beads includes first sustained-release beads and second sustained-release beads;
wherein the composition of active ingredients in the first sustained-release beads is different from the composition of active ingredients in the second sustained-release beads; and
wherein the first sustained-release beads release the at least one or more active ingredients contained therein at a rate different from the rate at which the second sustained-release beads release the one or more active ingredients contained therein.