IP Library › Granted Patent US 10,017,470
Granted Patent B2
US 10,017,470 · App. 13/978,791 · Granted Jul 10, 2018

Treatment for lipodystrophy

Inventors: Dhiraj Gambhire (Gujarat, IN); Rajendrakumar Hariprasad Jani (Gujarat, IN); Bipin Pandey (Gujarat, IN); Kaushik Sata (Gujarat, IN); Himanshu Kothari (Gujarat, IN); Pankaj Ramanbhai Patel (Gujarat, IN)
Assignee: Cadila Healthcare Limited
C07D207/333A61K31/40A61K45/06A61K9/2009A61K9/2013
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Quick Facts
Patent No.
US 10,017,470
App. No.
13/978,791
Granted
Jul 10, 2018
Kind
B2
Abstract

The present invention provides a therapeutic compound of formula (I) and their pharmaceutically acceptable salts for the prevention and treatment of lipodystrophy caused because of HIV infection or combination therapy of HIV-1 protease inhibitors (Pis) and/or reverse transcriptase inhibitors (nRTIs) by neutralizing lipohypertrophy, lipoatrophy and metabolic abnormalities in HIV patient.

Claims (6)

1. A method for treating lipodystrophy in a subject in need thereof, the method comprising

administering an effective amount of a compound of formula (I)

to the subject thereby to treat the lipodystrophy.

2. The method of claim 1 , wherein the lipodystrophy is HIV associated lipodystrophy.

3. The method of claim 2 , wherein the HIV associated lipodystrophy causes lipohypertrophy, lipoatrophy or a metabolic abnormality.

4. The method of claim 1 further comprising administering to the subject the compound of formula (I) in combination with a second therapeutic agent.

Assignments (3)
CHANGE OF NAME Recorded May 1, 2024
From: CADILA HEALTHCARE LIMITED
To: ZYDUS LIFESCIENCES LIMITED
Reel/Frame 067278/0662 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 16, 2024
From: CADILA HEALTHCARE LIMITED
To: ZYDUS LIFESCIENCES LIMITED
Reel/Frame 067116/0854 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 4, 2013
From: GAMBHIRE, DHIRAJ; JANI, RAJENDRAKUMAR HARIPRASAD; PANDEY, BIPIN; SATA, KAUSHIK; KOTHARI, HIMANSHU; PATEL, PANKAJ RAMANBHAI
To: CADILA HEALTHCARE LIMITED
Reel/Frame 031137/0212 →
Priority Claims (1)
IN 257/MUM/2011 · Jan 31, 2011 · national
Continuity (1)
Related Publication 20130338209A1 · Dec 19, 2013