IP Library Granted Patent US 9,512,389
Granted Patent B2
US 9,512,389 · App. 13/994,632 · Granted Dec 6, 2016

Hop oxidation-reaction product, preparing method thereof and use thereof

Inventors: Yoshimasa Taniguchi (Yokohama, JP); Yumie Kobayashi (Yokohama, JP); Fumitoshi Manabe (Yokohama, JP); Mikio Katayama (Yokohama, JP)
Assignee: Kirin Holdings Kabushiki Kaisha
C12C3/06A23L1/3002A61K36/185A61K2236/10
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Quick Facts
Patent No.
US 9,512,389
App. No.
13/994,632
Granted
Dec 6, 2016
Kind
B2
Abstract

The present invention relates to a hop extract having a reduced bitter taste which shows a fat absorption suppressing effect. More specifically the present invention relates to a hop extract oxidation-reaction product obtained by an oxidation-reaction of a hop extract.

Claims (19)

1. A method of suppressing lipid absorption comprising: providing a powdery mixture comprising a hop extract and a base material,

oxidizing the powdery mixture to obtain the hop extract oxidation-reaction product, and

administering an effective amount of the hop extract oxidation-reaction product to a mammal including human,

wherein the hop extract oxidation-reaction product comprises at least one of the components or component groups (A), (B), (C), (D), (E), (F):

(A) α acid

(B) iso α acid

(C) β acid

(D) Oxi-Fr.1

(E) Oxi-Fr.2

(F) β1, β2, β3, β4

wherein each weight ratio of (A) to (F) is (D)/((A)+(B))>0.1 or more, or (F)/(C)>0.3 or more, or (E)/(C)>2 or more.

2. The method according to claim 1 , wherein the hop extract is obtained by extracting a starting material selected from the group consisting of hop, a hop cone, ground product thereof, and combination thereof with supercritical carbon dioxide or an organic solvent.

3. The method according to claim 1 , wherein the base material is selected from the group consisting of food and food additives.

4. The method according to claim 3 , wherein the base material is at least one selected from the group consisting of saccharides, polysaccharides, inorganic carriers and brewing raw materials.

5. The method according to claim 1 , wherein the base material is at least one selected from the group consisting of starch, dextrin, cyclodextrin, cellulose, diatomaceous earth, perlite, activated earth, activated carbon, silica gel, synthetic adsorption resin, a hop and hop lees.

6. The method according to claim 1 , wherein a weight ratio of the hop extract and the base material is 1:1 to 1:10.

7. The method according to claim 1 , the method further comprising: isolating the hop extract oxidation-reaction product from the oxidized powdery mixture.

8. The method according to claim 1 , wherein the hop extract comprises at least one component selected from α acid and iso α acid.

9. The method according to claim 1 , wherein the hop extract further comprises β acid.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 7, 2013
From: TANIGUCHI, YOSHIMASA; KOBAYASHI, YUMIE; MANABE, FUMITOSHI; KATAYAMA, MIKIO
To: KIRIN HOLDINGS KABUSHIKI KAISHA
Reel/Frame 030964/0732 →
Priority Claims (1)
JP 2010-279933 · Dec 15, 2010 · national
Continuity (1)
Related Publication 20130316068A1 · Nov 28, 2013