IP Library › Granted Patent US 10,376,485
Granted Patent B2
US 10,376,485 · App. 14/002,809 · Granted Aug 13, 2019

Metabolic syndrome ameliorating agent

Inventors: Zhi-hong Yang (Tokyo, JP); Hiroko Miyahara (Tokyo, JP); Shuhei Takemura (Tokyo, JP); Akimasa Hatanaka (Tokyo, JP)
Assignee: NIPPON SUISAN KAISHA, LTD.
A61K31/201A23L33/115A61K31/231A61K35/60
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Quick Facts
Patent No.
US 10,376,485
App. No.
14/002,809
Granted
Aug 13, 2019
Kind
B2
Abstract

A method for ameliorating metabolic syndrome may include administering, to a patient in need thereof, an effective amount of a monounsaturated fatty acid having 22 carbons or a salt or an ester thereof and/or an effective amount of a monounsaturated fatty acid having 20 carbons or a salt or an ester thereof.

Claims (12)

1. A method of raising blood adiponectin concentrations, and lessening TNF-α concentration comprising administering, to a patient in need thereof,

an oil comprising an effective amount of at least one selected from (a) a monounsaturated fatty acid having 22 carbons, or a salt or an ester thereof, and (b) a monounsaturated fatty acid having 20 carbons, or a salt or an ester thereof,

wherein total amount of (a) the monounsaturated fatty acid having 22 carbons, or a salt or ester thereof, and (b) the monounsaturated fatty acid having 20 carbons, or a salt or an ester thereof is at least 50% by weight of total amount of all fatty acids present in the oil.

2. The method according to claim 1 , wherein the method comprises administering a glyceride of at least one selected from (a) the monounsaturated fatty acid having 22 carbons and (b) the monounsaturated fatty acid having 20 carbons.

3. The method according to claim 2 , wherein the glyceride is contained in a fish oil.

4. The method according to claim 1 , wherein the oil is contained in a food product.

5. The method according to claim 1 , wherein the method comprises administering an effective amount of a monounsaturated fatty acid having 22 carbons or a salt or an ester thereof, wherein the monounsaturated fatty acid having 22 carbons is docosenoic acid.

6. The method according to claim 1 , wherein the monounsaturated fatty acid having 20 carbons is icosenoic acid.

7. The method according to claim 1 , wherein the oil comprises an ester of (a) the monounsaturated fatty acid having 22 carbons and/or (b) the monounsaturated fatty acid having 20 carbons, and the oil is derived from a fish of the family Scomberesocidae, Gadidae, Salmonidae, Osmeridae, or Clupeidae.

8. The method according to claim 7 , wherein the oil is saury fish oil, or Alaska pollock oil.

9. The method according to claim 7 , the oil is MUFA-concentrated.

10. The method according to claim 1 , wherein the method comprises administering an oil comprising an effective amount of (a) the monounsaturated fatty acid having 22 carbons, or a salt or an ester thereof, and (b) the monounsaturated fatty acid having 20 carbons, or a salt or an ester thereof.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 13, 2013
From: YANG, ZHI-HONG; MIYAHARA, HIROKO; TAKEMURA, SHUHEI; HATANAKA, AKIMASA
To: NIPPON SUISAN KAISHA, LTD.
Reel/Frame 031592/0639 →
Priority Claims (3)
JP 2011-047313 · Mar 4, 2011 · national
JP 2011-110227 · May 17, 2011 · national
JP 2011-205318 · Sep 20, 2011 · national
Continuity (1)
Related Publication 20140066508A1 · Mar 6, 2014
Cited By (2)
US 12,331,564 US 12,723,448