Methods and apparatus for luminal stenting
Described herein are flexible implantable occluding devices that can, for example, navigate the tortuous vessels of the neurovasculature. The occluding devices can also conform to the shape of the tortuous vessels of the vasculature. In some embodiments, the occluding devices can direct blood flow within a vessel away from an aneurysm or limit blood flow to the aneurysm. Some embodiments describe methods and apparatus for adjusting, along a length of the device, the porosity of the occluding device. In some embodiments, the occluding devices allows adequate blood flow to be provided to adjacent structures such that those structures, whether they are branch vessels or oxygen-demanding tissues, are not deprived of the necessary blood flow.
1. A delivery system, comprising:
a catheter;
a delivery wire;
a self-expanding occluding device disposed on the delivery wire and within the catheter, the device being releasable from the delivery wire and the catheter and implantable across an aneurysm in a blood vessel of a patient, the device comprising:
a proximal end;
a distal end;
a length of the device extending between the proximal end and the distal end;
a lumen extending the length of the device; and
a plurality of strands braided together, a first plurality of said strands formed of first materials comprising a cobalt-nickel alloy, and a second plurality of said strands formed of second materials different from the first materials, the second materials comprising a platinum-tungsten alloy;
wherein the device has a porosity between said strands configured to direct blood flow away from an aneurysm and to allow blood flow to branch vessels when placed in a blood vessel;
wherein the device is self-expandable from a compressed state to an expanded state when released from the delivery wire and the catheter;
wherein the length of the device in the expanded state is shorter than the length of the device in the compressed state;
wherein the diameter of each of the plurality of strands is between about 0.0005 inches and 0.0020 inches;
wherein each of the plurality of strands comprises an inner surface and an outer surface, the outer surfaces comprising between about 20 percent and about 50 percent of the total circumferential area of the device in the expanded state; and
wherein a linear density of the plurality of strands is at least 74.04 picks per inch along the length of the device in the expanded state.
2. The device of claim 1 , wherein the porosity is between 70% and 80% in the expanded state.
3. The device of claim 1 , wherein the device has a lattice density between 20% and 50% in the expanded state.
4. The device of claim 1 , wherein the device has a coverage of 33% in the expanded state.
5. The device of claim 1 , wherein the plurality of strands comprises 48 strands.
6. The device of claim 1 , wherein the device has a diameter between 2.75 mm and 4.25 mm.
7. The device of claim 1 , wherein the cobalt-nickel alloy comprises 35NLT.
8. The device of claim 1 , wherein the platinum-tungsten alloy comprises 8% tungsten.
9. The device of claim 1 , wherein each said strand has a circular cross-section.
10. The device of claim 9 , wherein each said strand has a diameter between 0.001 inches and 0.0014 inches.
11. The device of claim 1 , wherein each said strand has an oval cross-section.
12. The device of claim 1 , wherein each said strand has a rectangular cross-section.
13. The device of claim 1 , wherein the plurality of strands are braided in a 1 over 1 under 1 pattern.
14. The device of claim 1 , wherein the plurality of strands are braided in a 1 over 2 under 2 pattern.
15. A delivery system, comprising:
a catheter;
a delivery wire;
a self-expanding occluding device disposed on the delivery wire and within the catheter, the device being releasable from the delivery wire and the catheter and implantable across an aneurysm in a blood vessel of a patient, the device comprising:
a length between a proximal end of the device and a distal end of the device;
a lumen extending along at least a portion of the length; and
a plurality of strands braided together, a first plurality of said strands formed of first materials comprising a cobalt-nickel alloy, and a second plurality of said strands formed of second materials different from the first materials, the second materials comprising a platinum-tungsten alloy;
wherein the device has a porosity between said strands configured to direct blood flow away from an aneurysm and to allow blood flow to branch vessels when placed in a blood vessel;
wherein the device is self-expandable from a compressed diameter in a compressed state to an expanded diameter, greater than the compressed diameter, in an expanded state when released from the delivery wire and the catheter;
wherein the diameter of each of the plurality of strands is between about 0.0005 inches and 0.0020 inches;
wherein each of the plurality of strands comprises an inner surface and an outer surface, the outer surfaces comprising between about 20 percent and about 50 percent of the total circumferential area of the device in the expanded state; and
wherein a linear density of the plurality of strands is at least 74.04 picks per inch along the length of the device in the expanded state.
16. The device of claim 15 , wherein the porosity is between 70% and 80% in the expanded state.
17. The device of claim 15 , wherein the device has a diameter between 2.75 mm and 4.25 mm.
18. The device of claim 15 , wherein the cobalt-nickel alloy comprises 35NLT.
19. The device of claim 15 , wherein the platinum-tungsten alloy comprises 8% tungsten.
20. The device of claim 15 , wherein each said strand has a diameter between 0.001 inches and 0.0014 inches.