Stable peracid-containing compositions
Methods have been developed for incorporation of peracid compounds and related compositions into a non-aqueous medium. The peracid incorporated into the non-aqueous medium is stable and keeps its chemical and antimicrobial activity for extended durations. The non-aqueous medium may be removed just prior to or during application of the peracid.
1. A stable peracid composition comprising a dissolvable non-aqueous medium and a peracid composition, the peracid composition comprising:
a carboxylic acid;
the peracid of said carboxylic acid;
a peroxy α-ketocarboxylic acid; and
an oxidizer,
wherein the peracid composition is impregnated in, suspended in, or attached to the dissolvable non-aqueous medium.
2. The stable peracid composition according to claim 1 , wherein the dissolvable non-aqueous medium further comprises a dissolvable polymer.
3. The stable peracid composition according to claim 1 , wherein the dissolvable non-aqueous medium is in a form of film, pellets, granules, bars, powders, gels, meshes, colloids, liposomes, micelles, or carbon nanostructures.
4. The stable peracid composition according to claim 1 , wherein the dissolvable non-aqueous medium is adapted to release the peracid composition upon contact of the stable peracid composition with water.
5. The stable peracid composition according to claim 4 , wherein the dissolvable non-aqueous medium is adapted to be immobilized on a boronic acid capture resin when the stable peracid composition is exposed to the boronic capture resin and water.
6. The stable peracid composition according to claim 1 , wherein the dissolvable non-aqueous medium is adapted to release the peracid composition upon contact of the stable peracid composition with an alcohol-based fluid.
7. The stable peracid composition according to claim 1 , wherein the dissolvable non-aqueous medium is adapted to release the peracid composition upon contact of the stable peracid composition with polyethylene glycol, PEG.
8. The stable peracid composition according to claim 1 , wherein the non-aqueous medium comprises pullulan.
9. A composition comprising:
a dissolvable polymer;
a carboxylic acid;
the peracid of said carboxylic acid;
a peroxy α-ketocarboxylic acid; and
an oxidizer impregnated in the dissolvable polymer.
10. The composition according to claim 9 , wherein the dissolvable polymer is in a form of a film, pellets, granules, bars, powders, gels, meshes, colloids, liposomes, micelles, or carbon nanostructures.
11. A method of stabilizing a peracid compound comprising:
mixing the peracid compound with a dissolvable polymer in an aqueous solution; and
drying the mixture to make a peracid-containing composition.
12. The method according to claim 11 , wherein the peracid composition comprises a carboxylic acid, the peracid of said carboxylic acid, a peroxy α-ketocarboxylic acid and an oxidizer.
13. A method for sterilizing, disinfecting, or sanitizing hard or porous surfaces or fabrics comprising:
dissolving a stable composition comprising a non-aqueous medium containing a film polymer, a carboxylic acid, the peracid of said carboxylic acid, a peroxy α-ketocarboxylic acid and an oxidizer;
separating the non-aqueous medium from the peracid;
removing the film polymer from the peracid; and
applying the peracid on the surfaces or fabrics.
14. The method of claim 13 , wherein the peracid is separated in the presence of polyethylene glycol.
15. The method of claim 13 , wherein the peracid is separated in the presence of an alcohol.
16. The method of claim 13 , wherein the peracid is separated in the presence of water.
17. The method of claim 13 , wherein the film polymer is separated prior to the application of the peracid on surfaces, fabrics, or instruments.
18. The method of claim 13 , wherein the separated peracid is applied on medical instruments, consumer products or industrial instruments for disinfection or sterilization.
19. The method of claim 13 , wherein the separated peracid is applied on hard or porous surfaces for disinfection or sterilization.
20. The method of claim 13 , wherein the separated peracid is applied on fabrics for disinfection or sterilization.
21. The stable peracid composition according to claim 1 , wherein the carboxylic acid is acetic acid and the peracid of said carboxylic acid is peracetic acid.
22. The stable peracid composition according to claim 1 , wherein the peroxy a-ketocarboxylic acid is peroxy pyruvic acid.
23. The stable peracid composition according to claim 1 , wherein the oxidizer is hydrogen peroxide.
24. The stable peracid composition according to claim 2 , wherein the dissolvable polymer is a mixture of pullulan and sodium alginate.
25. The stable peracid composition according to claim 2 , wherein the dissolvable polymer is a mixture of pullulan and sodium alginate, the carboxylic acid is acetic acid and the peracid of said carboxylic acid is peracetic acid, the peroxy α-ketocarboxylic acid is peroxy pyruvic acid, and the oxidizer is hydrogen peroxide.