IP Library Granted Patent US 9,150,559
Granted Patent B2
US 9,150,559 · App. 14/117,571 · Granted Oct 6, 2015

Anti-proliferative compounds and methods for using the same

Inventors: Michael L. Cleary (Eugene, OR); Christina Matheny (San Francisco, CA)
Assignee: The Board of Trustees of the Leland Stanford Junior University
C07D413/12C07D263/32
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Quick Facts
Patent No.
US 9,150,559
App. No.
14/117,571
Granted
Oct 6, 2015
Kind
B2
Abstract

Disclosed herein are anti-proliferative compounds which find use in inhibiting the growth of cancer cells. Also provided herein are methods for using these compounds for inhibiting growth of cancer cells. Also provided herein are methods for using these compounds for treating a subject for hyperproliferative conditions, including without limitation the treatment of hematopoietic cancers.

Claims (1)

1. A method of inhibiting the growth of leukemia cells, wherein the leukemia cells comprise a genetic abnormality in the MLL gene, the method comprising contacting the leukemia cells with an effective dose of a compound of the structure:

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 14, 2014
From: CLEARY, MICHAEL L.; MATHENY, CHRISTINA
To: THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY
Reel/Frame 033308/0153 →
CONFIRMATORY LICENSE Recorded Jan 10, 2014
From: THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 031969/0243 →
Continuity (2)
Provisional Application 61488103 · May 19, 2011
Related Publication 20140323524A1 · Oct 30, 2014