Peptides from chaperonin 60.1
Peptides from the polypeptide chaperonin 60.1, and their use in medicine for the treatment of inflammatory conditions are described.
1. An isolated or recombinant peptide molecule consisting of the amino acid sequence selected from the group:
(SEQ ID NO: 2)
(i)
DGSVVVNKVSELPAGH;
(SEQ ID NO: 3)
(ii)
GLNVNTLSYGDLAAD;
(SEQ ID NO: 4)
(iii)
SELPAGHGLNVNLTS;
(SEQ ID NO: 5)
(iv)
DGSVVVNKVS;
(SEQ ID NO: 6)
(v)
ELPAGHGLNV;
and
(SEQ ID NO: 7)
(vi)
NTLSYGDLAAD.
2. The isolated or recombinant peptide molecule according to claim 1 , consisting of the amino acid sequence DGSVVVNKVSELPAGH (SEQ ID NO: 2).
3. The isolated or recombinant peptide molecule according to claim 1 , consisting of the amino acid sequence GLNVNTLSYGDLAAD (SEQ ID NO: 3).
4. The isolated or recombinant peptide molecule according to claim 1 , consisting of the amino acid sequence SELPAGHGLNVNLTS (SEQ ID NO: 4).
5. A pharmaceutical composition comprising a peptide molecule according to claim 1 and a pharmaceutically-acceptable excipient.
6. An adjuvant system comprising (i) a peptide molecule according to claim 1 and (ii) an antigen.