IP Library Granted Patent US 9,211,541
Granted Patent B2
US 9,211,541 · App. 14/123,824 · Granted Dec 15, 2015

Nucleic acid amplification apparatus and nucleic acid analysis apparatus

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Quick Facts
Patent No.
US 9,211,541
App. No.
14/123,824
Granted
Dec 15, 2015
Kind
B2
Abstract

According to a conventional technique, when a calibrated temperature measuring probe is used for correcting the temperature absolute values of individually temperature-controllable thermal control blocks, a temperature difference of a maximum of 0.5° C. remains between the thermal control blocks. According to the present invention, the melting temperature of a temperature calibration sample housed in a reaction vessel corresponding to each of the temperature control blocks is measured as a measured melting temperature. The measured melting temperature corresponding to each of the thermal control blocks and the reference melting temperature of the temperature calibration sample are compared, and the temperature absolute value of each of the thermal control blocks is corrected based on respective difference values.

Claims (17)

1. A testing system comprising:

a network information database;

an information management apparatus connected to the network information database;

two or more genetic testing systems each including a plurality of temperature control units, the genetic testing systems being connected via a network to the network information database; and

a service management apparatus connected to the information management apparatus and to the genetic testing systems via the network,

wherein the information management apparatus:

distributes temperature calibration sample information via the network information database to the two or more genetic testing systems,

automatically identifies one of the temperature control units with abnormal fluid temperature control in one of the two or more genetic testing systems,

controls the two or more genetic testing systems such that the one of the temperature control units with the abnormal fluid temperature control is removed from a testing area during normal testing or a testing result thereof is not used, and

supplies information about the one of the two or more genetic testing systems which has the one of the temperature control units with the abnormal fluid temperature control to the service information management apparatus when the abnormal fluid temperature control is identified,

wherein each of the two or more genetic testing systems receives the same temperature calibration sample information and compares the temperature calibration sample information with a measured temperature obtained by performing a predetermined temperature calibration with the plurality of temperature control units of each of the two or more genetic testing systems, and

wherein the temperature control units of each of the two or more genetic testing systems correct the measured temperature to be substantially the same temperature in each of the two or more genetic testing systems.

2. The testing system according to claim 1 , wherein the predetermined temperature calibration includes measurement of a melting temperature of a temperature calibration sample as the measured temperature.

3. The testing system according to claim 1 ,

wherein the service information management apparatus receives temperature calibration result information of each of the genetic testing systems connected via the network via the information management apparatus, and

wherein the information management apparatus centrally manages the temperature calibration result information of the genetic testing systems.

4. The testing system according to claim 1 , wherein the temperature calibration sample information is a melting temperature of a temperature calibration sample.

Assignments (2)
CHANGE OF NAME AND ADDRESS Recorded Mar 30, 2020
From: HITACHI HIGH-TECHNOLOGIES CORPORATION
To: HITACHI HIGH-TECH CORPORATION
Reel/Frame 052259/0227 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 4, 2013
From: MAEDA, KOHSHI; SUGIYAMA, CHIE; SHOJI, YOSHIYUKI; ISHIZAWA, MASATO; SANO, MINORU
To: HITACHI HIGH-TECHNOLOGIES CORPORATION
Reel/Frame 031713/0730 →