IP Library › Granted Patent US 9,434,766
Granted Patent B2
US 9,434,766 · App. 14/129,758 · Granted Sep 6, 2016

CCR2 antagonist peptides

Inventors: Christophe Combadiere (Magny le Hongre, FR); Florian Sennlaub (Paris, FR); Constance Auvynet (Paris, FR); Sylvian Chemtob (Cote St Luc, CA); Christiane Quiniou (Montreal, CA)
Assignee: Universite Pierre Et Marie Curie (Paris 6)
C07K7/08C07K7/06C07K14/7158A61K38/00
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Quick Facts
Patent No.
US 9,434,766
App. No.
14/129,758
Granted
Sep 6, 2016
Kind
B2
Abstract

The invention relates to a peptide comprising the following amino acid sequence Thr-Phe-Leu-Lys (SEQ ID NO: 17) or Thr-Phe-Leu-Lys-Cys (SEQ ID NO: 1), useful as a CCR2 non-competitive antagonist peptide.

Claims (6)

1. A peptide that consists of LGTFLKC (SEQ ID NO:3).

2. The peptide of claim 1 , wherein all or part of the amino acids are in D configuration.

3. The peptide of claim 1 , wherein all or part of the amino acids are in L configuration.

4. A compound that comprises a peptide as defined in claim 1 linked to at least one non-peptide moiety.

5. The compound of claim 4 , wherein the non-peptide moiety is polyethylene gycol.

6. A pharmaceutical composition, comprising the peptide as defined in claim 1 , in association with a pharmaceutically acceptable carrier.

Assignments (2)
MERGER Recorded Oct 29, 2018
From: UNIVERSITÉ PIERRE ET MARIE CURIE (PARIS 6)
To: SORBONNE UNIVERSITE
Reel/Frame 047336/0714 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 27, 2016
From: COMBADIERE, CHRISTOPHE; SENNLAUB, FLORIAN; AUVYNET, CONSTANCE; CHEMTOB, SYLVAIN; QUINIOU, CHRISTIANE
To: UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6)
Reel/Frame 039267/0341 →
Priority Claims (1)
EP 11305816 · Jun 27, 2011 · regional
Continuity (1)
Related Publication 20150011477A1 · Jan 8, 2015