Systems for comprehensive fourier domain optical coherence tomography (FDOCT) and related methods
Optical coherence tomography systems for imaging a whole eye are provided including a sample arm including focal optics that are configured to rapidly switch between at least two scanning modes in less than about 1.0 second.
1. An optical coherence tomography system for imaging a whole eye, the system comprising:
a sample arm including focal optics configured to switch between at least two scanning modes,
wherein the at least two scanning modes comprise an anterior segment scanning mode and a retinal scanning mode;
wherein the sample arm of the system in retinal scanning mode comprises a collimator, a two-axis scanning mirror assembly, and a scan lens assembly, and an objective lens; and
wherein the focal optics of the sample arm are configured to reposition at least one movable lens to change an optical coherence tomography (OCT) scan beam from a collimated beam for imaging an emmetropic eye to one of a converging beam for imaging a myopic eye and a diverging beam for imaging a hyperopic eye;
a mechanical means for modifying components within an optical pathway of the sample arm to switch the scanning mode between the retinal scanning mode and the anterior segment scanning mode; and
a reference arm coupled to the sample arm and comprising a means for discrete switching between two path delays in coordination with switching between the at least two scanning modes,
wherein a first path delay is configured to match an optical path length of the OCT scan beam in the retinal scanning mode and a second path delay is configured to match an optical path length of the OCT scan beam in anterior segment scanning mode,
wherein the sample arm of the system in the anterior segment scanning mode comprises a collimating lens, two two-axis scanning mirror assemblies, a scan lens, an objective lens and a curved mirror placed a focal length (f) away from a first of the two two-axis scanning mirror assemblies; and
wherein a second of the two two-axis scanning mirror assemblies is configured to direct re-directed collimated light in a triangular pattern towards the curved mirror causing the optical path length of the system to be longer in the anterior segment scanning mode than in the retinal scanning mode.
2. An optical coherence tomography system for imaging a whole eye, the system comprising:
a sample arm including focal optics configured to switch between at least two scanning modes,
wherein the at least two scanning modes comprise an anterior segment scanning mode and a retinal scanning mode;
wherein the sample arm of the system in retinal scanning mode comprises a collimator, a two-axis scanning mirror assembly, and a scan lens assembly, and an objective lens; and
wherein the focal optics of the sample arm are configured to reposition at least one movable lens to change an optical coherence tomography (OCT) scan beam from a collimated beam for imaging an emmetropic eye to one of a converging beam for imaging a myopic eye and a diverging beam for imaging a hyperopic eye;
a mechanical means for modifying components within an optical pathway of the sample arm to switch the scanning mode between the retinal scanning mode and the anterior segment scanning mode; and
a reference arm coupled to the sample arm and comprising a means for discrete switching between two path delays in coordination with switching between the at least two scanning modes,
wherein a first path delay is configured to match an optical path length of the OCT scan beam in the retinal scanning mode and a second path delay is configured to match an optical path length of the OCT scan beam in anterior segment scanning mode,
wherein the sample arm of the system in the anterior segment scanning mode comprises a collimating lens, a two-axis scanning mirror assembly, a scan lens, an objective lens, a flat mirror and a concave mirror placed a focal length (f) away from the two-axis scanning mirror assembly, wherein light incident on the two-dimensional scanner pair is deviated such that the an incident collimated beam is directed into a separate path consisting of the flat mirror and the concave mirror.