Fluid System Health Monitor

A fluidic system comprising a force-transfer fluidic system with at least one fluidic component comprising a TDG sensor comprising in some embodiments an oxygen sensor, a luminescent oxygen sensor, or an electrochemical oxygen sensor. The system may further comprise a pressure transducer, a chamber and a membrane forming at least a portion of the chamber wall, the membrane being in direct or indirect contact with fluid or gas above the fluid. The TDG sensor may comprise control logic and an output of the control logic may be used directly or indirectly to control at least one process parameter of the system, including pressure and flow rate, and the control logic also may be used to notify the need for purification or to alert that a certain purity has been achieved.