Re-epithelialization wound dressings and systems
Methods, apparatuses, and systems for promoting re-epithelialization as an aspect of wound healing are presented. A re-epithelialization dressing for use with reduced pressure has a moist tissue-interface layer, a manifold member, and a sealing member. The moist tissue-interface layer has a plurality of apertures. The moist tissue-interface layer is for disposing adjacent to the wound and provides a moisture balance (i.e., provides moisture when the wound is dry and receives moisture when the wound site is substantially wet). The reduced pressure, apertures, and moist tissue-interface layer help with liquid management and otherwise promote re-epithelialization. Other systems, apparatuses, and methods are presented.
1. A method for promoting re-epithelialization of a wound, the method comprising the steps of:
deploying a re-epithelialization dressing proximate to the wound, wherein the re-epithelialization dressing comprises:
a moist tissue-interface layer operable to provide a moisture balance, the moist tissue-interface layer comprising an absorptive, water-based material having a first side and a second, tissue-facing side, wherein the absorptive, water-based material of the moist tissue-interface layer is porous and comprises a plurality of apertures that provide a plurality of routes of fluid communication through the absorptive, water-based material of the moist tissue-interface layer between the first side and the second, tissue-facing side, and wherein the plurality of apertures have a variable diameter dependent upon moisture absorbed by the absorptive, water-based material, such that the plurality of apertures decrease in diameter to move from an open position to a restricted position with an increase in the moisture absorbed,
wherein each of the plurality of apertures is perforated and extends through the moist tissue-interface layer between the first side and the second, tissue-facing side of the absorptive, water-based material,
a foam manifold member for distributing reduced pressure, the foam manifold member having a first side and a second, tissue-facing side,
a sealing member, the sealing member having a first side and a second, tissue-facing side and for forming a sealed space, and
wherein the foam manifold member is disposed between the sealing member and the moist tissue-interface layer;
fluidly coupling a reduced-pressure source to the sealed space; and
providing reduced pressure to the sealed space.
2. The method for promoting re-epithelialization of a wound of claim 1 , wherein fluidly coupling a reduced-pressure source to the sealed space comprises coupling a reduced-pressure connector to the sealing member and fluidly coupling a reduced-pressure delivery conduit to the reduced-pressure connector and the reduced-pressure source.
3. The method for promoting re-epithelialization of a wound of claim 1 , wherein the absorptive, water-based material comprises a hydrogel layer.
4. The method for promoting re-epithelialization of a wound of claim 1 , wherein the absorptive, water-based material comprises a hydrocolloid layer.
5. The method for promoting re-epithelialization of a wound of claim 1 , wherein the absorptive, water-based material comprises a hydrogel-impregnated foam layer.
6. The method for promoting re-epithelialization of a wound of claim 1 , wherein the re-epithelialization dressing further comprises a support layer having a first side and a second-tissue facing side, wherein the second-tissue facing side of the support layer is disposed adjacent to the first side of the moist tissue-interface layer.
7. The method for promoting re-epithelialization of a wound of claim 1 , wherein the re-epithelialization dressing further comprises a support layer having a first side and a second-tissue facing side, wherein the second-tissue facing side of the support layer is coupled to the first side of the absorptive, water-based material.
8. The method for promoting re-epithelialization of a wound of claim 1 , wherein the re-epithelialization dressing further comprises an absorbent layer disposed between the manifold member and the sealing member.
9. The method for promoting re-epithelialization of a wound of claim 1 , wherein the re-epithelialization dressing further comprises: a support layer having a first side and a second-tissue facing side, wherein the second-tissue facing side of the support layer is disposed adjacent to the first side of the absorptive, water-based material; and an absorbent layer disposed between the first side of the manifold member and the second, tissue-facing side of the sealing member.
10. The method for promoting re-epithelialization of a wound of claim 1 , wherein the re-epithelialization dressing further comprises a support layer having a plurality of apertures, each of the plurality of apertures of the support layer aligning and substantially corresponding to one of the apertures of the absorptive, water-based material.
11. The method for promoting re-epithelialization of a wound of claim 1 , wherein the re-epithelialization dressing further comprises a support layer comprised of an occlusive film material.
12. The method for promoting re-epithelialization of a wound of claim 1 , wherein the re-epithelialization dressing further comprises a support layer adapted to hold a first end of the plurality of apertures of the absorptive, water-based material in an open position or with a constant diameter.
13. The method for promoting re-epithelialization of a wound of claim 1 , further comprising a support layer disposed between the manifold member and the moist tissue-interface layer, the support layer having a plurality of apertures, each of the apertures of the support layer substantially corresponding to one of the apertures of the absorptive, water-based material, wherein the support layer is coupled to the moist tissue-interface layer and adapted to hold an end of at least one of the plurality of apertures of the absorptive, water-based material in an open position or with a constant diameter.
14. The method for promoting re-epithelialization of a wound of claim 1 , wherein the second, tissue-facing side of the absorptive, water-based material is smooth and adapted to substantially preclude micro-strain at the wound.
15. The method for promoting re-epithelialization of a wound of claim 1 , wherein the reduced-pressure is between about −25 mm Hg and −75 mm Hg and adapted to substantially preclude micro-strain at the wound.
16. The method for promoting re-epithelialization of a wound of claim 1 , wherein the second, tissue-facing side of the absorptive, water-based material is smooth, and wherein the reduced-pressure is between about −25 mm Hg and −75 mm Hg, thereby substantially precluding micro-strain at the wound.
17. The method for promoting re-epithelialization of a wound of claim 1 , wherein the manifold member comprises a reticulated open-cell foam.
18. The method for promoting re-epithelialization of a wound of claim 1 , wherein the apertures of the absorptive, water-based material are configured to swell to a substantially restricted position under the influence of increasing moisture, wherein the apertures in the restricted position are configured to allow liquid to pass and to restrict gas from passing, wherein the second, tissue-facing side of the absorptive, water-based material is smooth, and wherein the reduced-pressure is between about −25 mm Hg and −75 mm Hg, thereby substantially precluding micro-strain at the wound.
19. The method for promoting re-epithelialization of a wound of claim 1 , wherein the reduced-pressure is between about −25 mm Hg and −75 mm Hg.
20. The method for promoting re-epithelialization of a wound of claim 1 , wherein the plurality of apertures are in a uniform pattern within the absorptive, water-based material.
21. The method for promoting re-epithelialization of a wound of claim 1 , wherein one or more of the plurality of apertures is formed with a laser, or punched, or drilled, or formed by casting.
22. The method for promoting re-epithelialization of a wound of claim 1 , wherein the diameter of one or more of the plurality of apertures is selected so that the one or more of the plurality of apertures close completely to restrict the passing of gases in the restricted position.
23. The method for promoting re-epithelialization of a wound of claim 1 , wherein one or more of the plurality of apertures have a first end with a constant diameter and also have at least a portion with the variable diameter dependent upon moisture absorbed by the absorptive, water-based material.