IP Library Granted Patent US 9,726,742
Granted Patent B2
US 9,726,742 · App. 14/171,310 · Granted Aug 8, 2017

System and method for iteratively calibrated reconstruction kernel for accelerated magnetic resonance imaging

Inventors: Steen Moeller (Minneapolis, MN); Edward Auerbach (Minneapolis, MN); Kamil Ugurbil (Minneapolis, MN); Essa Yacoub (Hudson, WI)
Assignee: Regents of the University of Minnesota
G01R33/561G01R33/4835G01R33/56341
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Quick Facts
Patent No.
US 9,726,742
App. No.
14/171,310
Granted
Aug 8, 2017
Kind
B2
Abstract

A method for iteratively calibrating a reconstruction kernel for use in accelerated magnetic resonance imaging (MRI) is provided. An MRI system is used to acquire k-space data from multiple slice locations following the application of a multiband radio frequency (RF) excitation pulse. An initial reconstruction kernel is generated from the acquired k-space data, and this initial reconstruction kernel is used to produce an initial image for each of the multiple slice locations by applying the initial reconstruction kernel to the acquired k-space data. The average phase of each slice location is then calculated from these images, and used to shift the phase values of the subsequently acquired k-space data. From the phase-shifted k-space data, an updated reconstruction kernel is then generated. This process is repeated iteratively until a stopping criterion is satisfied.

Claims (17)

1. A method for reconstructing an image using a magnetic resonance imaging (MRI) system, the steps of the method comprising:

a) acquiring, using the MRI system, first k-space data from a plurality of different slice locations, wherein spins in each slice location are excited using a single band radio frequency (RF) excitation pulse;

b) acquiring, using the MRI system, second k-space data from the plurality of different slice locations, wherein spins in the plurality of different slice locations are excited using a multiband RF excitation pulse;

c) generating an initial reconstruction kernel from the first k-space data acquired in step a);

d) producing an initial image for each of the multiple slice locations by applying the initial reconstruction kernel generated in step c) to the second k-space data acquired in step b);

e) producing an updated reconstruction kernel by deriving one of phase information and magnitude information from the initial images produced in step d), generating updated k-space data by applying the derived one of phase information and magnitude information to the first k-space data, and generating the updated reconstruction kernel from the updated k-space data; and

f) producing an image for each slice location by applying the updated reconstruction kernel to the second k-space data acquired in step b).

2. The method as recited in claim 1 , wherein step e) includes deriving phase information from the initial images and applying the phase information to the first k-space data to produce phase-shifted k-space data.

3. The method as recited in claim 2 , wherein the phase information includes an average phase value calculated for each slice location from the respective initial image for that slice location.

4. The method as recited in claim 3 , wherein calculating the average phase value includes averaging phase values over each channel in a multichannel receiver.

5. The method as recited in claim 4 , wherein calculating the average phase value includes averaging over each spatial frequency in addition to over each channel in the multichannel receiver.

6. The method as recited in claim 2 , wherein the phase information includes a spatially varying phase value calculated from the initial images.

7. The method as recited in claim 2 , wherein the phase-shifted k-space data is produced by producing phase-shifted images by multiplying the initial images produced in step d) by the phase information, and Fourier transforming the phase-shifted images into k-space.

8. The method as recited in claim 1 , wherein the second k-space data acquired in step b) is undersampled along a phase-encoding direction.

9. The method as recited in claim 1 , wherein steps d) and e) are repeated to iteratively update the reconstruction kernel until a stopping criterion is satisfied.

10. The method as recited in claim 1 , wherein the initial reconstruction kernel generated in step c) includes a first initial reconstruction kernel and a second initial reconstruction kernel, the first initial reconstruction kernel being associated with a first portion of k-space and the second initial reconstruction kernel being associated with a second portion of k-space that is different that the first portion of k-space.

11. The method as recited in claim 10 , wherein the first portion of k-space is associated points in k-space where a source point is matched and spatially aligned with a target point, and the second portion of k-space is associated with points in k-space where a source point is matched but not spatially aligned with a target point.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 10, 2017
From: MOELLER, STEEN
To: REGENTS OF THE UNIVERSITY OF MINNESOTA
Reel/Frame 042956/0642 →
CONFIRMATORY LICENSE Recorded Feb 27, 2014
From: REGENTS OF THE UNIVERSITY OF MINNESOTA
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 032365/0914 →
Continuity (2)
Provisional Application 61759865 · Feb 1, 2013
Related Publication 20140218026A1 · Aug 7, 2014