System for non-invasive heart treatment
The invention provides a non-invasive method for treatment of arrhythmia. In a first aspect, a method for treatment of atrial fibrillation in a heart of a patient comprises directing radiation from outside the patient toward one or more target treatment regions of the heart so as to inhibit the atrial fibrillation. The radiation may induce isolation of a pulmonary vein.
1. A system for treatment of atrial fibrillation in a heart of a patient, the system comprising:
a source of particle beam radiation or x-ray radiation; and
a system comprising a computer processor having a means for treating atrial fibrillation by directing the particle beam radiation or x-ray radiation from outside the patient toward one or more target treatment regions in the heart of the patient so as to inhibit the atrial fibrillation, the system coupled to the source of particle beam radiation or x-ray radiation.
2. The system of claim 1 , further comprising computer software defining a planned plurality of radiation beams for transmission relative to a planning image of the heart so as to induce an arrhythmia-inhibiting lesion pattern, the computer software coupled to the computer processor.
3. The system of claim 2 , further comprising a tomography or magnetic resonance imaging system for acquiring the planning image of the heart, the imaging system to the computer processor.
4. The system of claim 1 , further comprising a registration imaging system coupled to the computer processor so that the computer processor dynamically registers the planned plurality of radiation beams with one or more target treatment regions of the heart of the patient during treatment.
5. The system of claim 1 , further comprising a robot supporting the source of particle beam radiation or x-ray radiation, the robot moving the source of particle beam radiation or x-ray radiation relative to the patient so as to orient the particle beam radiation or x-ray radiation toward the heart of the patient per the planned plurality of radiation.
6. The system of claim 2 , wherein the planned plurality of radiation beams defined by the computer software are configured to converge on the one or more target treatment regions in the heart of the patient.
7. The system of claim 6 , wherein the planned plurality of radiation beams defined by the computer software are configured to ablate linear lesions within the heart sufficient to inhibit an electrical pathway.
8. The system of claim 7 , wherein the linear lesions correspond to a Maze lesion pattern.
9. The system of claim 2 , wherein the planned plurality of radiation beam are configured to effect bilateral pulmonary vein isolation.
10. The system of claim 2 , wherein the planned plurality of radiation beams are configured to target at least one ectopic focus of the heart.
11. The system of claim 2 , wherein the planned plurality of radiation beams defined by the computer software are configured to avoid exceeding a tolerance of an identified tissue structure adjacent to the one or more target regions.
12. The system of claim 2 , wherein the planned plurality of radiation beams defined by the computer software comprise a number, intensity, and direction of the planned plurality of radiation beams.
13. The system of claim 1 , wherein the source of particle beam radiation or x-ray radiation comprises a plurality of gamma radiation sources that emit gamma radiation directed at target points at a center of radiation focus.
14. The system of claim 13 , wherein the plurality of gamma radiation sources are included in a shielded array unit.
15. The system of claim 2 , wherein the source of—particle beam radiation or x-ray radiation comprises a linear accelerator mounted to a maneuverable robotic arm having at least six degrees of freedom.
16. The system of claim 15 , wherein the computer processor further comprises an image guidance system comprising two fixed diagnostics fluoroscopes to provide a stationary frame of reference for locating the heart of the patient relative to the robotic arm and the linear accelerator.
17. The system of claim 1 , wherein the source of particle beam radiation or x-ray radiation is included in a stereotactic system.
18. The system of claim 3 , further comprising a display configured to output the planning image of the heart designating a three-dimensional location of the one or more target treatment regions in the heart of the patient.