IP Library Granted Patent US 9,295,683
Granted Patent B2
US 9,295,683 · App. 14/204,592 · Granted Mar 29, 2016

Omega-3 phospholipid supplements for improved brain maturity

Inventors: Kjetil Berge (Oslo, NO); Lena Burri (Oslo, NO)
Assignee: AKER BIOMARINE ANTARCTIC AS
A61K31/661A23J7/00A23L1/29A23L1/30A23L1/3006A61K31/194A61K31/23A23V2002/00
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Quick Facts
Patent No.
US 9,295,683
App. No.
14/204,592
Granted
Mar 29, 2016
Kind
B2
Abstract

The invention relates to omega-3 phospholipid supplements for use in adolescents, and in particular to use omega-3 phospholipid supplements to improve or support brain maturity age. In preferred embodiments, the omega-3 phospholipid is krill oil.

Claims (17)

1. A method of improving or supporting brain maturity age in a subject in need thereof comprising:

administering an omega-3 phospholipid supplement to said subject under conditions such that the brain maturity age of the subject is improved, wherein said brain maturation age is calculated by comparison of EEG measurements with reference EEG measurements.

2. The method of claim 1 , wherein said omega-3 phospholipid supplement is a krill oil, fish oil, fish roe oil, or fish byproduct oil.

3. The method of claim 2 , wherein said krill oil comprises from about 35% to 60% phospholipids on a w/w basis; from about 20% to 45% triglycerides on a w/w basis; and from about 50 to about 2500 mg/kg astaxanthin.

4. The method of claim 1 , wherein said omega-3 phospholipid supplement comprises EPA and DHA.

5. The method of claim 1 , wherein said subject is an adolescent.

6. The method of claim 5 , wherein said adolescent is a male.

7. The method of claim 1 , wherein said administration is oral.

8. The method of claim 1 , wherein said omega-3 phospholipid supplemented is administered a daily dosage of from about 3 grams to about 6 grams per day.

9. The method of claim 8 , wherein said daily dose is administered in two doses of from 1.5 to 3 grams in the morning and evening.

10. The method of claim 1 , wherein said subject has been diagnosed with ADHD.

11. A method of improving or supporting brain maturity age in a subject in need thereof comprising:

administering a krill oil supplement to said subject under conditions such that the brain maturity age of the subject is improved, wherein said krill oil supplement comprises from about 35% to 60% phospholipids on a w/w basis, from about 20% to 45% triglycerides on a w/w basis, and from about 50 to about 2500 mg/kg astaxanthin, and wherein said brain maturation age is calculated by comparison of EEG measurements with reference EEG measurements.

12. The method of claim 11 , wherein said subject is an adolescent male.

13. The method of claim 11 , wherein said administration is oral.

14. The method of claim 11 , wherein said omega-3 phospholipid supplemented is administered a daily dosage of from about 3 grams to about 6 grams per day.

15. The method of claim 14 , wherein said daily dose is administered in two doses of from 1.5 to 3 grams in the morning and evening.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 16, 2015
From: AKER BIOMARINE AS
To: AKER BIOMARINE ANTARCTIC AS
Reel/Frame 034739/0819 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 11, 2014
From: BERGE, KJETIL; BURRI, LENA
To: AKER BIOMARINE AS
Reel/Frame 032407/0333 →
Continuity (2)
Provisional Application 61783574 · Mar 14, 2013
Related Publication 20140274968A1 · Sep 18, 2014