IP Library Granted Patent US 9,102,668
Granted Patent B2
US 9,102,668 · App. 14/251,778 · Granted Aug 11, 2015

Polymorphs and salts

Inventors: Julie Nicole Hamblin (Stevenage, GB); Paul Spencer Jones (Stevenage, GB); Suzanne Elaine Keeling (Stevenage, GB); Joelle Le (Stevenage, GB); Charlotte Jane Mitchell (Stevenage, GB); Nigel James Parr (Stevenage, GB); Robert David Willacy (Stevenage, GB)
Assignee: Glaxo Group Limited
C07D413/14
View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 9,102,668
App. No.
14/251,778
Granted
Aug 11, 2015
Kind
B2
Abstract

The present invention is directed to novel polymorphs and salts of a compound which is an inhibitor of kinase activity.

Claims (4)

1. A polymorph (Form II) of N-[5-[4-(5-{[(2R,6S)-2,6-dimethyl-4-morpholinyl]methyl}-1,3-oxazol-2-yl)-1H-indazol-6-yl]-2-(methyloxy)-3-pyridinyl]methanesulfonamide characterised in that it provides an XRPD pattern comprising a peak at (°2θ) 9.2+/−0.1.

2. A polymorph according to claim 1 characterised in that it provides an XRPD pattern comprising peaks substantially as set out in Table 1.

3. A polymorph according to claim 1 in that it provides an XRPD pattern substantially in accordance with FIG. 1 .

4. A pharmaceutical composition comprising a polymorph as defined in claim 1 and one or more pharmaceutically acceptable excipients.

Assignments (2)
CHANGE OF ADDRESS Recorded Apr 16, 2025
From: GLAXO GROUP LIMITED
To: GLAXO GROUP LIMITED
Reel/Frame 071044/0904 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 31, 2014
From: GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED
To: GLAXO GROUP LIMITED
Reel/Frame 033452/0594 →
Continuity (3)
Continuation 13821585
Provisional Application 61380748 · Sep 8, 2010
Related Publication 20140256721A1 · Sep 11, 2014