Chromen-2-one derivatives and their use as monoamine neurotransmitter re-uptake inhibitors
The present application discloses novel 8-aza-bicyclo[3.2.1]oct-3-yloxy)-chromen-2-one derivatives useful as monoamine neurotransmitter re-uptake inhibitors. In other aspects the application discloses the use of these compounds, a method for therapy and to pharmaceutical compositions comprising these compounds.
1. A compound of Formula (I):
wherein R 1 is methoxy, or a pharmaceutically acceptable salt thereof.
2. The compound according to claim 1 , which is exo-7-[(-8-azabicyclo[3.2.1]octan-3-yl)oxy]-3-methoxy-chromen-2-one hydrochloride.
3. A pharmaceutical composition, comprising a therapeutically effective amount of a compound, or a pharmaceutically acceptable salt thereof according to claim 1 , together with at least one pharmaceutically acceptable carrier, excipient or diluent.