IP Library › Patent Application 14272404
Patent Application
App. No. 14/272,404

Activated T Cells

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Quick Facts
Patent No.
US None
App. No.
14/272,404
Abstract

Provided are compositions comprising activated T cells and activated T cells armed with bispecific antibodies directed at cancer antigens which are poor responders to alloantigen, and methods of using the compositions to help engraftment and improve anti-tumor effects.

Claims (4)

1 . A composition comprising cord blood mononuclear cells wherein said cord mononuclear cells do not react to allo-antigens on other cord bloods.

2 . A composition comprising cord blood T cells and other mononuclear cell components in cord blood wherein said cord blood T cells and other mononuclear cell components in cord blood do not react to allo-antigens in adult peripheral blood on other cord bloods.

3 . A composition comprising anti-CD3 activated cord blood T cells and other activated mononuclear cell components in cord blood wherein said anti-CD3 activated cord blood T cells and other activated mononuclear cell components in cord blood do not react to allo-antigens on other cord bloods.

4 - 11 . (canceled)