IP Library Patent Application 14287769
Patent Application
App. No. 14/287,769

SYSTEMS AND METHODS THAT PROVIDE ELECTRICAL STIMULATION TO A NERVE TO REDUCE A REFLEX THAT AFFECTS A BODILY FUNCTION

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Quick Facts
Patent No.
US None
App. No.
14/287,769
Abstract

One aspect of the present disclosure relates to a system for electrical stimulation. A waveform generator can be configured to generate an electrical waveform. An electrode can be electrically coupled to the waveform generator and configured to deliver the electrical waveform to a nerve to reduce at least one reflex that affects a bodily function.

Claims (28)

1 . A system comprising:

a waveform generator configured to generate an electrical waveform; and

an electrode configured to deliver the electrical waveform to stimulate a nerve to reduce at least one reflex that affects a bodily function.

2 . The system of claim 1 , wherein the at least one reflex comprises a urethral reflex.

3 . The system of claim 2 , wherein the urethral reflex is at least one of a reflex controlling an external urethral sphincter or a reflex controlling an internal urethral sphincter.

4 . The system of claim 2 , wherein the urethral reflex impedes the bodily function.

5 . The system of claim 4 , wherein the bodily function comprises voiding the urinary bladder.

6 . The system of claim 5 , further comprising a bladder driver configured to selectively void the urinary bladder when the urethral reflexes are reduced.

7 . The system of claim 6 , wherein the bladder driver is configured to apply electrical stimulation to at least one of a sacral root, a bladder efferent nerve, and an afferent-mediated peripheral nerve to activate the urinary bladder for voiding.

8 . The system of claim 1 , wherein the electrode is a surface electrode or a subcutaneous electrode.

9 . The system of claim of claim 1 , wherein the nerve is at least one of a peripheral nerve, a sacral spinal cord nerve, a sacral root nerve, and a lumber spinal cord nerve.

10 . The system of claim 9 , wherein the nerve comprises an afferent nerve fiber.

11 . The system of claim 1 , wherein the electrical waveform comprises a base frequency, wherein the stimulation is delivered during a period of the base frequency,

12 . A method for affecting a bodily function in a subject, the method comprising the steps of:

generating, by a waveform generator, an electrical waveform; and

delivering, by an electrode coupled to the waveform generator, the electrical waveform to a nerve comprising an afferent nerve fiber of the subject to stimulate the afferent nerve fiber to affect the bodily function.

13 . The method of claim 12 , wherein the electrode is a surface electrode or a subcutaneous electrode.

14 . The method of claim 12 , wherein the electrical waveform comprises a burst waveform.

15 . The method of claim 12 , wherein the electrical waveform stimulates the afferent nerve to reduce urethral reflexes that impede urine flow.

16 . The method of claim 15 , wherein the bodily function comprises voiding the urinary bladder.

17 . The method of claim 16 , further comprising stimulating, by a bladder driver, a second nerve to activate the urinary bladder to facilitate the voiding when the urethral reflexes are reduced.

18 . A neural prosthesis for providing urinary bladder control in a subject, the neural prosthesis comprising:

a waveform generator configured to generate an electrical waveform configured to reduce at least one urethral reflex that impedes urine flow from a urinary bladder of the subject; and

an electrode configured to deliver the electrical waveform to a nerve of the subject;

wherein the electrical waveform causes the nerve to generate at least one action potential to reduce the at least one urethral reflex and facilitate voiding of the urinary bladder.

19 . The neutral prosthesis of claim 18 , wherein the electrode is a surface electrode or a subcutaneous electrode.

20 . The neural prosthesis of claim 18 , wherein the nerve comprises an afferent nerve fiber, and

wherein the electrical waveform is configured to stimulate an afferent nerve to reduce the urethral reflex.

Assignments (2)
CONFIRMATORY LICENSE Recorded Aug 29, 2018
From: CASE WESTERN RESERVE UNIVERSITY
To: NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR NIH
Reel/Frame 046734/0111 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 1, 2014
From: BHADRA, NARENDRA; GUSTAFSON, KENNETH J.; MCCOIN, JAIME L.
To: CASE WESTERN RESERVE UNIVERSITY
Reel/Frame 033218/0664 →