IP Library Granted Patent US 9,228,995
Granted Patent B2
US 9,228,995 · App. 14/301,782 · Granted Jan 5, 2016

Method and apparatus for measuring hematocrit of blood

Inventors: Sung Yang (Gwangju, KR); Myounggon Kim (Gwangju, KR)
Assignee: GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY
G01N33/49G01N27/02G01N27/06G01N27/07G01N27/08
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Quick Facts
Patent No.
US 9,228,995
App. No.
14/301,782
Granted
Jan 5, 2016
Kind
B2
Abstract

Disclosed herein are a method and an apparatus for measuring hematocrit of flowing blood. The apparatus for measuring hematocrit of blood according to an exemplary embodiment of the present invention includes: a body part provided with a blood inlet and a blood outlet; first and second electrodes disposed on both inner side walls of the body part so as to be opposite to each other; a third electrode disposed on the same side wall as a side wall on which the first electrode is disposed while maintaining a predetermined distance from the first electrode; a measurement unit measuring first impedance of blood between the first and second electrodes and second impedance of the blood between the first and third electrodes; and a calculation unit determining the hematocrit of blood using the first and second impedances.

Claims (11)

1. An apparatus for measuring hematocrit of blood, the apparatus comprising:

a body part provided with a first inner side wall opposite a second inner sidewall, a blood inlet and a blood outlet;

a first electrode disposed on the first inner side wall, and a second electrode disposed on the second inner side wall, wherein the first electrode and the second electrode are opposite to each other;

a third electrode disposed on the first inner side wall and disposed a predetermined distance from the first electrode;

a measurement unit configured to measure a first impedance of blood between the first and second electrodes and a second impedance of the blood between the first and third electrodes; and

a calculation unit configured to determine hematocrit of blood using the first and second impedances, wherein the calculation unit is configured to calculate a first and a second hematocrit estimation parameter by determining a ratio of the impedance of plasma and a sum of the impedance of plasma and the impedance of cytoplasm, wherein the impedance of plasma and the impedance of cytoplasm of the blood are determined using the first and second impedance measurements, determining a normalized difference between the first and second hematocrit estimation parameters, and determining the hematocrit of the blood using both the first hematocrit estimation parameter and the normalized difference.

2. A method for measuring hematocrit of blood, the method comprising:

measuring, using an apparatus comprising a body part provided with a first inner side wall opposite a second inner sidewall, a blood inlet and a blood outlet; a first electrode disposed on the first inner side wall, and a second electrode disposed on the second inner side wall, wherein the first electrode and the second electrode are opposite to each other; and a third electrode disposed on the first inner side wall and disposed a predetermined distance from the first electrode; a first impedance of blood between first and second electrodes;

measuring a second impedance of the blood between the first electrode and a third electrode;

calculating a first and a second hematocrit estimation parameter by determining a ratio of the impedance of plasma and a sum of the impedance of plasma and the impedance of cytoplasm, wherein the impedance of plasma and the impedance of cytoplasm of the blood are determined using the first and second impedance measurements, determining a normalized difference between the first and second hematocrit estimation parameters, and

determining the hematocrit of the blood using both the first hematocrit estimation parameter and the normalized difference.

Assignments (3)
MERGER Recorded May 14, 2018
From: QBIOSENS INC.
To: RADIANQBIO CO. LTD.
Reel/Frame 046148/0158 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 12, 2017
From: GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY
To: QBIOSENS INC.
Reel/Frame 043564/0995 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 11, 2014
From: YANG, SUNG; KIM, MYOUNGGON
To: GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY
Reel/Frame 033133/0993 →
Priority Claims (1)
KR 10-2014-0028721 · Mar 12, 2014 · national
Continuity (1)
Related Publication 20150260705A1 · Sep 17, 2015