REDOX SIGNALING GEL FORMULATION

1 . A gel formulation comprising;

a. a composition comprising at least one reactive oxygen species (ROS), and

b. a rheology modifier;

wherein the process of making the composition comprises the steps of purifying water to produce ultra-pure water, combining a salt to the ultra-pure water to create a salinated water, electrolyzing the salinated water at a temperature of from 4.3 to 5.8° C. wherein the electrolyzing is accomplished with an anode, cathode and power source such that a) the power source comprises a transformer and a rectifier and does not comprise a filter capacitor and b) no membrane is used between the anode and cathode during the process of electrolyzing.

2 . The formulation of claim 1 , wherein the at least one reactive oxygen species (ROS) is a superoxide.

3 . The formulation of claim 1 , wherein the at least one reactive oxygen species (ROS) is hypochlorous acid or a salt thereof.

4 . The formulation of claim 1 , wherein the at least one reactive oxygen species (ROS) is present at an amount of at least 25% of its original concentration after 1 year.

5 . The formulation of claim 1 , wherein the process is a scaled up process.

6 . The formulation of claim 1 , wherein the salt is sodium chloride.

7 . The formulation of claim 1 , wherein the process includes a pulsating voltage such that the voltage is 0 at least 30 times per second and the voltage remains positive at all times.

8 . The formulation of claim 1 , wherein the gel has a pH between 6 and 9.

9 . The formulation of claim 1 , wherein the composition comprises:

a. sodium present at a concentration of 1000 to 1400 ppm wherein the sodium is measured by inductively coupled plasma mass spectrometry (ICP-MS),

b. chloride present at a concentration from 1200 to 1600 ppm as wherein the chloride is measured by inductively coupled plasma mass spectrometry (ICP-MS) or chloride is present at a concentration from 0 to 1 ppm wherein the chloride is measured by 35 Cl nuclear magnetic resonance ( 35 Cl NMR),

c. hypochlorous acid present at a concentration of 16 to 24 ppm wherein the hypochlorous acid is measured by colorimetry or hypochlorous acid present at a concentration of 2300 to 2700 ppm wherein the hypochlorous acid is measured by 25 Cl nuclear magnetic resonance ( 25 Cl NMR),

d. superoxide radical present at a concentration of 94 uM wherein the superoxide radical is measured by 5-(Diisopropoxyphosphoryl)-5-1-pyrroline-N-oxide nuclear magnetic resonance (DIPPMPO-NMR) or no superoxide radical, and

e. hydroxyl radical present at a concentration of 241 uM wherein the hydroxyl xeradical is measured by DIPPMPO-NMR or hydroxyl radical present at a concentration of 0 to 10 ppm wherein the hydroxyl radical is measured by mass spectrometry (MS) or no hydroxyl radical.

10 . The formulation of claim 9 , wherein the sodium, chloride, hypochlorous acid, superoxide radical and hydroxyl radical are measured less than one year after the composition was made.

11 . The formulation of claim 9 , wherein the sodium, chloride, hypochlorous acid, superoxide radical and hydroxyl radical are present at any time within 1 year after the composition was made.

12 . The formulation of claim 9 , wherein the sodium, chloride, hypochlorous acid, superoxide and hydroxyl radical are measured at different times.

13 . The formulation of claim 9 , wherein the sodium, chloride, hypochlorous acid, superoxide radical and hydroxyl radical are measured at the same time.

14 . The formulation of claim 1 , wherein the rheology modifier comprises SiO 2 , MgO, Li 2 O, and Na 2 O.

15 . The formulation of claim 1 , wherein the rheology modifier comprises a crosslinked acrylic acid polymer.

16 . The formulation of claim 1 , wherein the composition has an electron paramagnetic resonance (EPR) spectrum as shown in FIG. 13 .