Granted Patent
B2
US 9,315,483 · App. 14/340,143 · Granted Apr 19, 2016
Synthesis of deuterated catechols and benzo[D][1,3]dioxoles and derivatives thereof
Inventors:
Andrew D. Jones (Needham, MA); Robert E. Zelle (Stow, MA); I. Robert Silverman (Arlington, MA)
Assignee:
Concert Pharmaceuticals, Inc.
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Abstract
The present invention provides a convenient and efficient process for the synthesis of d 2 -benzo[d][1,3]dioxoles.
Claims (7)
1. A compound represented by the following structural formula:
wherein:
the isotopic enrichment of the compound with deuterium is at least 99.0%;
n is 1, 2 or 3;
each R 1 is independently —OR a or —CHO; and
R a is —H or a phenol protecting group.
2. The compound of claim 1 wherein the compound is represented by the following structural formula:
Assignments (2)
MERGER
Recorded Aug 2, 2023
From: CONCERT PHARMACEUTICALS, INC.
To: SUN PHARMACEUTICAL INDUSTRIES, INC.
Reel/Frame 064465/0383 →
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Sep 18, 2014
From: JONES, ANDREW D; ZELLE, ROBERT E; SILVERMAN, I ROBERT
To: CONCERT PHARMACEUTICALS, INC.
Reel/Frame 033765/0088 →
Continuity (3)
Provisional Application
60993565
· Sep 13, 2007