IP Library Granted Patent US 9,791,398
Granted Patent B2
US 9,791,398 · App. 14/343,376 · Granted Oct 17, 2017

Measurement device with sensor array

Inventors: William Clark (Wexford, PA); Sung Kwon Cho (Pittsburgh, PA); Yuejun Zhao (Pittsburgh, PA); Timothy J. Syciarz (Pittsburgh, PA); R. Maxwell Flaherty (Auburndale, FL); J. Christopher Flaherty (Auburndale, FL); David W. Wagner (Boston, MA)
Assignee: pHase2 microtechnologies, Inc.
G01N27/302B01L3/502738G01N27/28G01N27/307B01L2200/027B01L2200/0673B01L2300/0645B01L2300/087B01L2300/0816B01L2300/0829B01L2300/1827B01L2400/0406B01L2400/049B01L2400/0427B01L2400/0677G01N27/4035G01N33/4836
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Quick Facts
Patent No.
US 9,791,398
App. No.
14/343,376
Granted
Oct 17, 2017
Kind
B2
Abstract

A system for obtaining a pH measurement includes a disposable probe and a reader. The disposable probe comprises multiple indicating electrodes and at least one reference electrode. The reader is configured to operably engage with the disposable probe and provide pH information of a sample.

Claims (26)

1. A system for obtaining a pH measurement of a sample comprising:

a disposable probe comprising:

a first chamber storing a reference solution;

a second chamber housing a reference electrode;

a third chamber surrounding an indicating electrode configured to be exposed to the sample, wherein the third chamber comprises a first orifice configured to be opened so as to expose the indicating electrode to the sample; and

a second orifice positioned between the first and second chambers, the second orifice configured to be opened so as to expose the reference solution to the reference electrode.

2. The system of claim 1 further comprising an electronics module constructed and arranged to activate at least one orifice.

3. The system of claim 2 wherein the electronics module comprises a lookup table that comprises orifice activation information.

4. The system of claim 2 comprising multiple electrodes configured to be exposed to the sample, and wherein the electronics module is constructed and arranged to allow an operator to individually activate each electrode in the multiple electrodes.

5. The system of claim 1 wherein at least one orifice comprises a membrane.

6. The system of claim 5 wherein the membrane comprises a multi-layer membrane.

7. The system of claim 5 wherein the membrane comprises a heating element constructed and arranged to create an opening in the membrane.

8. The system of claim 7 wherein at least a portion of the heating element is positioned in contact with the membrane.

9. The system of claim 1 wherein the at least one electrode comprises an iridium oxide electrode.

10. The system of claim 1 wherein the at least one electrode is manufactured using a MEMS process.

11. The system of claim 1 further comprising a liquid junction.

12. The system of claim 1 further comprising a substrate, and wherein the at least one electrode is positioned on and/or proximate to the substrate.

13. The system of claim 1 further comprising a reader constructed and arranged to operably engage with the disposable probe and provide pH information of the sample.

14. The system of claim 1 wherein each of the second and third chamber comprises a vacuum chamber constructed and arranged to draw a solution into the chamber.

15. The system of claim 1 wherein the first chamber is a fluidic closed loop channel.

16. A disposable probe comprising:

a first chamber storing a reference solution;

a second chamber housing a reference electrode;

a third chamber surrounding an indicating electrode configured to be exposed to a sample, wherein the third chamber comprises a first orifice configured to be opened so as to expose the indicating electrode to the sample; and

a second orifice positioned between the first and second chambers, the second assembly configured to be opened so as to expose the reference solution to the reference electrode.

17. The disposable probe of claim 16 wherein each of the first and second assembly comprises a membrane.

Assignments (1)
CORRECTION BY DECLARATION OF THE ASSIGNED PROVISIONAL APPL. NO. PREVIOUSLY RECORDED ON REEL 036941 FRAME 0219. DECLARANT HEREBY CONFIRMS THE ASSIGNED PROVISIONAL APPL. IS 61/531,238. Recorded Dec 7, 2015
From: PHASE2 MICROTECHNOLOGIES LLC
To: PHASE2 MICROTECHNOLOGIES LLC
Reel/Frame 037278/0926 →
Continuity (2)
Provisional Application 61531238 · Sep 6, 2011
Related Publication 20160003761A1 · Jan 7, 2016