IP Library › Granted Patent US 9,610,370
Granted Patent B2
US 9,610,370 · App. 14/350,194 · Granted Apr 4, 2017

Compositions and methods for tumor imaging and targeting by a class of organic heptamethine cyanine dyes that possess dual nuclear and near-infrared properties

Inventors: Leland W. K. Chung (Beverly Hills, CA); Dongfeng Pan (Charlottesville, VA)
Assignee: University of Virginia Patent Foundation
A61K51/0482A61B5/0035A61B5/0075A61B6/481A61K49/0032A61K49/0034A61K49/0438A61K51/0446C07B59/002C09B23/0016C09B23/0066C09B23/086A61K51/0474
View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 9,610,370
App. No.
14/350,194
Granted
Apr 4, 2017
Kind
B2
Abstract

The present invention provides for heptamethine cyanine dyes that possess both nuclear and near-infrared imaging capabilities. These dyes can be used for imaging, targeting and detecting tumors in patients.

Claims (2)

1. A Dual Nuclear/NIR Agent having one of the following structures:

2. A pharmaceutical composition comprising the Dual Nuclear/NIR Agent according to claim 1 , and at least one pharmaceutically acceptable carrier.

Assignments (3)
CONFIRMATORY LICENSE Recorded Apr 24, 2017
From: CEDARS-SINAI MEDICAL CENTER
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 042320/0778 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 17, 2014
From: PAN, DONGFENG
To: UNIVERSITY OF VIRGINIA
Reel/Frame 032694/0706 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 17, 2014
From: UNIVERSITY OF VIRGINIA
To: UNIVERSITY OF VIRGINIA PATENT FOUNDATION
Reel/Frame 032694/0800 →
Continuity (3)
Provisional Application 61544915 · Oct 7, 2011
Provisional Application 61605360 · Mar 1, 2012
Related Publication 20140248213A1 · Sep 4, 2014