Encapsulation of personal care actives
Described are methods for encapsulating a personal care active, comprising preparing an aqueous phase, comprising partially hydrolyzed polyvinyl alcohol and a cosmetically acceptable non-ionic surfactant, preparing an oil phase, comprising the personal care active and isocyanate or polyisocyanate, homogenizing the aqueous phase and oil phase to form an emulsion with particles less than one micron, and forming a dispersion of polyurea core-shell particles containing the personal care active by contacting the emulsion with an aqueous amine solution.
1. A method for encapsulating a personal care active, comprising:
preparing an aqueous phase, comprising partially hydrolyzed polyvinyl alcohol and a cosmetically acceptable non-ionic surfactant;
preparing an oil phase, comprising the personal care active and isocyanate or polyisocyanate;
homogenizing the aqueous phase and oil phase to form an emulsion; and
forming a dispersion of polyurea core-shell particles containing the personal care active by contacting the emulsion with an aqueous amine solution, wherein the polyurea core-shell particles have an average particle size in a range of from 100 nm to 0.49 micron.
2. The method of claim 1 , wherein the step of homogenizing excludes high pressure homogenization.
3. The method of claim 1 , wherein the emulsion particles have a single modal particle size distribution.
4. The method of claim 1 , wherein the non-ionic surfactant comprises ethylene oxide, propylene oxide, butylene oxide, fatty alcohol ethoxylates, fatty acid esters, alkoxylates of fatty acid esters, unsaturated polyalkoxyalkyl ethers, alkoxylated amines, ethylene oxide propylene oxide copolymers, fatty acid alkoxylates, tall oil, rosin ester alkoxylates, alkyl phenol alkoxylates or substituted phenol alkoxylates.
5. The method of claim 1 , wherein the non-ionic surfactant is polyoxyethylene alkyl ether or a secondary alcohol ethoxylate.
6. The method of claim 1 , wherein the surfactant is present in an amount of from about 1 to about 7.5 weight percent of the aqueous phase.
7. The method of claim 1 , wherein the partially hydrolyzed polyvinyl alcohol is present in an amount of from about 1 to about 15 weight percent of the aqueous phase.
8. The method of claim 1 , wherein the aqueous phase further comprises polyvinyl pyrrolidone, copolymers of vinyl pyrrolidone and acetate, copolymers of vinyl pyrrolidone, vinyl acetate and vinyl alcohol, copolymers of acrylic acid and polyethyleneoxide, copolymers of alkyl(meth)acrylate, lignosulphonate, copolymers of maleic anhydride and methyl vinyl ether, copolymers of maleic anhydride and diisobutylene, polystyrene sulphonate, polyalkyl cellulose or polycarboxyalkyl cellulose.
9. The method of claim 1 , wherein the personal care active is a sunscreen agent.
10. The method of claim 9 , wherein the sunscreen agent is paraminobenzoic acid, avobenzone, cinoxate, dioxybenzone, homosalate, menthyl anthranilate, octocrylene, octyl methoxycinnamate, octyl salicylate, oxybenzone, padimate O, phenylbenzimidazole sulfonic acid, sulisobenzone, trolamine salicylate, titanium dioxide and zinc oxide, diethanolamine methoxycinnamate, digalloy trioleate, ethyl dihydroxypropyl PABA, glyceryl aminobenzoate, lawsone with dihydroxy acetone, red petrolatum and any combinations thereof.