IP Library › Granted Patent US 9,296,728
Granted Patent B2
US 9,296,728 · App. 14/373,615 · Granted Mar 29, 2016

Therapeutic compounds

Inventors: Venkatram R. Mereddy (Minneapolis, MN); Lester R. Drewes (Minneapolis, MN); Mohammed Abrar Alam (Minneapolis, MN); Sravan K. Jonnalagadda (Minneapolis, MN); Shirisha Gurrapu (Minneapolis, MN)
Assignee: Regents of the University of Minnesota
C07D405/04C07C255/41C07C255/63C07D207/09C07D295/155C07D311/12C07D407/14
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Quick Facts
Patent No.
US 9,296,728
App. No.
14/373,615
Granted
Mar 29, 2016
Kind
B2
Abstract

The invention provides compounds of formula (I) or a salt thereof as described herein. The invention also provides pharmaceutical compositions comprising a compound of formula (I), processes for preparing compounds of formula (I), intermediates useful for preparing compounds of formula (I) and therapeutic methods for treating cancer or treating autoimmune diseases or preventing transplant rejection using compounds of formula (I).

Claims (13)

1. A compound of the formula:

or a salt thereof.

2. The compound of claim 1 which is:

or a salt thereof.

3. The compound of claim 1 which is:

or a salt thereof.

4. The compound of claim 1 which is:

or a salt thereof.

5. The compound of claim 1 which is:

or a salt thereof.

6. The compound of claim 1 which is:

or a salt thereof.

7. A composition comprising a compound of formula Ic as described in claim 1 , or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable diluent or carrier.

Assignments (3)
CONFIRMATORY LICENSE Recorded Jun 24, 2021
From: REGENTS OF THE UNIVERSITY OF MINNESOTA
To: THE GOVERNMENT OF THE UNITED STATES, AS REPRESENTED BY THE SECRETARY OF THE ARMY
Reel/Frame 056754/0017 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 4, 2015
From: ALAM, MOHAMMAD ABRAR
To: REGENTS OF THE UNIVERSITY OF MINNESOTA
Reel/Frame 035082/0535 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 5, 2014
From: MEREDDY, VENKATRAM R.; DREWES, LESTER R.; JONNALAGADDA, SRAVAN K.; GURRAPU, SHIRISHA
To: REGENTS OF THE UNIVERSITY OF MINNESOTA
Reel/Frame 034399/0616 →
Continuity (2)
Provisional Application 61589090 · Jan 20, 2012
Related Publication 20140371272A1 · Dec 18, 2014