Method for producing collagen-containing sheet material
A method for producing a collagen-containing sheet material, wherein a collagen-containing suspension is dried in such a manner that the collagen settles during drying and forms a transparent skin.
1. A method for producing a collagen-containing sheet material, comprising:
treating a mammalian skin starting material with wet chemicals;
mechanically comminuting the treated starting material into a slurry;
preparing an aqueous suspension of the comminuted, treated starting material from the slurry, said aqueous suspension having a solid content from 0.5 to 5%;
adjusting the pH of the aqueous suspension to a pH between 5.5 and 8;
transferring the aqueous suspension to a tray;
waiting until at least a portion of the suspension in the tray settles out before drying; and
drying the aqueous suspension in the tray such that a transparent film of the collagen-containing sheet material is formed having a closed porosity of less than 20%;
wherein said collagen-containing sheet material comprises more than 70% of collagen; and
wherein said collagen-containing sheet material has a thickness between 0.05 and 2 mm.
2. The method for producing a collagen-containing sheet material as claimed in claim 1 , wherein metal particles are added to the aqueous suspension.
3. The method for producing a collagen-containing sheet material as claimed in claim 2 , wherein metal particles are added as a suspension.
4. The method for producing a collagen-containing sheet material as claimed in claim 2 , wherein silver particles are added to the aqueous suspension.
5. The method for producing a collagen-containing sheet material as claimed in claim 2 , wherein the metal particles have an average particle size of less than 50 nm.
6. The method for producing a collagen-containing sheet material as claimed in claim 1 , wherein metal particles are added, which have an average particle size between 10 nm and 10 μm.
7. The method for producing a collagen-containing sheet material as claimed in claim 1 , wherein bactericidal agents are added to the aqueous suspension.
8. The method for producing a collagen-containing sheet material as claimed in claim 1 , wherein antifungal agents are added to the aqueous suspension.