IP Library Granted Patent US 9,073,931
Granted Patent B2
US 9,073,931 · App. 14/385,671 · Granted Jul 7, 2015

Liver X receptor modulators

Inventors: Katerina Leftheris (San Diego, CA); Linghang Zhuang (Chalfont, PA)
Assignee: Vitae Pharmaceuticals, Inc.
C07D487/04A61K31/4985
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Quick Facts
Patent No.
US 9,073,931
App. No.
14/385,671
Granted
Jul 7, 2015
Kind
B2
Abstract

Provided herein are novel compounds and pharmaceutically acceptable salts thereof that are liver X receptor modulators. Also provided are compositions comprising compounds of the invention and a carrier. Additionally, use of the compounds herein and methods for treating a disease or disorder associated with the liver X receptor are further described.

Claims (6)

1. A compound represented by the following structural formula:

or a pharmaceutically acceptable salt thereof.

2. A pharmaceutical composition comprising a pharmaceutical carrier or diluent and a compound represented by the following structural formula:

or a pharmaceutically acceptable salt thereof.

3. A method of treating a subject with dermatitis comprising administering an effective amount of a compound represented by the following structural formula:

or a pharmaceutically acceptable salt thereof to the subject.

Assignments (2)
CHANGE OF NAME Recorded Mar 20, 2019
From: VITAE PHARMACEUTICALS, INC.
To: VITAE PHARMACEUTICALS, LLC
Reel/Frame 050150/0044 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 17, 2014
From: DONG, CHENGGUO; FAN, YI; LEFTHERIS, KATERINA; LOTESTA, STEPHEN D.; SINGH, SURESH B.; TICE, COLIN M.; ZHAO, WEI; ZHENG, YAJUN; ZHUANG, LINGHANG
To: VITAE PHARMACEUTICALS, INC.
Reel/Frame 033757/0813 →
Continuity (2)
Provisional Application 61612063 · Mar 16, 2012
Related Publication 20150065515A1 · Mar 5, 2015