Composition for preventing or treating rheumatoid arthritis
The present disclosure relates to a composition for treating and preventing an rheumatoid arthritis, wherein the composition containing a peptide comprising amino acid sequence of SEQ ID NO: 1, a peptide having 80% or more sequence identity with the amino acid sequence of the peptide or a peptide which is a fragment thereof. According to the present invention, provided is a composition for prevention or treatment of rheumatoid arthritis having a superior effect of treating and preventing rheumatoid arthritis with minimized side effect.
1. A method for treatment of rheumatoid arthritis comprising administering to a subject in need thereof an effective amount of the isolated peptide of SEQ ID NO: 1.
2. The method according to claim 1 , wherein the peptide is administered in a single dose at a concentration of 0.001 ng/kg to 1 ng/kg.
3. The method according to claim 1 , wherein the peptide is administered in a single dose at a concentration of 0.01 ng/kg to 0.4 ng/kg.
4. The method according to claim 1 , wherein the peptide is administered once daily for 1 to 5 days.
5. The method according to claim 1 , wherein the peptide is administered 1 to 3 times a day.
6. The method of claim 1 , wherein the peptide is administered at a daily dose of 0.1 μg/kg to 1.0 g/kg.
7. The method of claim 6 , wherein the peptide is administered 1 to 3 times daily.
8. A method for treatment of rheumatoid arthritis comprising administering to a subject in need thereof a composition comprising the isolated peptide of SEQ ID NO: 1.
9. The method of claim 8 , wherein the composition is administered through oral, rectal, transdermal, intravenous, intramuscular, intraperitoneal, in the bone marrow, epidural, or subcutaneous means.
10. The method of claim 8 , wherein the composition comprises 0.1 μg/mg to 1 mg/mg of the isolated peptide.
11. The method according to claim 8 , wherein the peptide is administered in a single dose at a concentration of 0.001 ng/kg to 1 ng/kg.
12. The method according to claim 8 , wherein the peptide is administered in a single dose at a concentration of 0.01 ng/kg to 0.4 ng/kg.
13. The method according to claim 8 , wherein the peptide is administered once daily for 1 to 5 days.
14. The method according to claim 8 , wherein the peptide is administered 1 to 3 times a day.
15. The method of claim 8 , wherein the peptide is administered at a daily dose of 0.1 μg/kg to 1.0 g/kg.
16. The method of claim 15 , wherein the peptide is administered 1 to 3 times daily.