IP Library Granted Patent US 10,213,345
Granted Patent B2
US 10,213,345 · App. 14/401,702 · Granted Feb 26, 2019

Apparatus and process for providing a coiled collagen carrier

Inventors: Poul Bertelsen (Roskilde, DK); Henrik Neuschafer Larsen (Soborg, DK); Pernille Dybendal Pedersen (Frederiksberg, DK)
Assignee: TAKEDA AS
A61F13/0283A61F13/0276A61L24/102B29C53/32B29C53/52B29C53/8016A61L2300/252A61L2300/418A61L2400/04
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Quick Facts
Patent No.
US 10,213,345
App. No.
14/401,702
Granted
Feb 26, 2019
Kind
B2
Abstract

The present invention relates inter alia to an apparatus for providing a coiled collagen carrier. An apparatus according to the invention preferably comprises a device for applying moisture to a collagen carrier prior to coiling of the collagen carrier and a coiling device. The coiling device preferably comprises rotatable gripping means for gripping the collagen carrier along an edge and coiling the collagen carrier, and a support device supporting the collagen carrier while being coiled. In another aspect, the invention relates to a production facility wherein an apparatus according to invention is arranged.

Claims (25)

1. An apparatus for providing one or more coiled collagen carriers each configured for application to a patient, the apparatus comprising:

a device for applying moisture to a collagen carrier so as to moisturise the collagen carrier; and

a coiling device to which the moisturised collagen carrier is conveyed from the moisturising device, the coiling device comprising:

a pair of elongated members for gripping along an edge of the moisturised collagen carrier and coiling the moisturised collagen carrier in a lengthwise or widthwise direction thereof to produce the coiled collagen carrier; and

a support device comprising a tray defining a cavity within which said coiling takes place by the rotatable gripping means, said cavity formed by wall segments of the tray against which the moisturised collagen carrier is supported during said coiling, wherein the support device maintains the coiled shape of the moisturised collagen carrier within the apparatus downstream of the coiling device.

2. The apparatus according to claim 1 , wherein the pair of elongated members is a pair of tweezers or pincers.

3. The apparatus according to claim 1 , wherein the tray cavity is provided with a bottom shaped as a cylindrical segment and with at least one open end, and wherein a curved part of the cylindrical segment extends at least 180 °.

4. The apparatus according to claim 3 , wherein the cavity is channel-shaped, with the wall segments parallel to one another and extending from the bottom of the cavity.

5. The apparatus according to claim 3 ,

wherein the elongated members extend into the cavity during said coiling through at least one of the at least one open end.

6. The apparatus according to claim 1 , wherein the apparatus is further configured to move the pair of elongated members in reciprocating movement so that the elongated members can be retracted from the collagen carrier after said coiling.

7. The apparatus according to claim 1 , further comprising a compressing device selected from the group consisting of a pair of rollers, a pair of even plates, or a rolling object and flat bottom plate, the compressing device configured to compress the moisturised collagen carrier prior to said coiling of the moisturised collagen carrier.

8. The apparatus according to claim 7 , wherein the compressing device comprises the pair of rollers.

9. The apparatus according to claim 8 , wherein one or both of the rollers are mounted such that the rollers are configured to move apart, said mounting allowing displacement of the one or both rollers in a direction perpendicular to the axis of rotation of the one or both rollers, and wherein the rollers are biased towards each other.

10. The apparatus according to claim 7 , further comprising at least one air-conditioning device maintaining the atmosphere surrounding the collagen carrier at a temperature of 18-22° C. and a relative humidity of 30-50% during said moisturising, compressing, and coiling.

11. The apparatus according to claim 7 , further comprising at least one drying means selected from the group consisting of a drying tunnel, a pump sucking or blowing air, and a desiccator, the drying means arranged downstream of the coiling device so as to dry the coiled collagen carrier subsequent to said coiling.

12. The apparatus according to claim 1 , further comprising at least one drying means selected from the group consisting of a drying tunnel, a pump sucking or blowing air, and a desiccator, the drying means arranged downstream of the coiling device so as to dry the coiled collagen carrier subsequent to said coiling.

13. The apparatus according to claim 12 , wherein the drying means comprises the drying tunnel through which the coiled collagen carrier is conveyed while being supported by the support device.

14. The apparatus according to claim 1 , further comprising a first conveyer device conveying the collagen carrier downstream of the moisturiser device and towards the coiling device prior to said coiling.

15. The apparatus according to claim 14 , further comprising a pair of rollers arranged to compress the moisturised collagen carrier prior to said coiling of the moisturised collagen carrier, wherein the first conveyer device conveys the moisturised collagen carrier to the pair of rollers.

16. The apparatus according to claim 15 , wherein the first conveyer device comprises a first conveying element and a second conveying element, the first conveying element conveying the collagen carrier towards the moisturiser device, and the second conveying element conveying the moisturised collagen carrier downstream of the moisturiser device and towards the pair of rollers.

17. The apparatus according to claim 16 , wherein more than one of said tray cavity is provided, each of the tray cavities configured to support said coiling of a respective one of said collagen carriers, and said tray being arranged on and conveyed by a second conveyer device of the apparatus.

18. The apparatus according claim 1 , further comprising a cabinet sealing at least one of the moisturiser device and the coiling device.

19. The apparatus according to claim 1 , further comprising a device for conveying the coiled collagen carrier from the support device and arranging it in an inner container.

20. A production facility in which the apparatus according to claim 1 is arranged in a primary production room of the facility sealed by airlocks.

Assignments (3)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 13, 2021
From: TAKEDA AS
To: TOPAZ INVESTMENT AS
Reel/Frame 057936/0082 →
CHANGE OF NAME Recorded Jan 12, 2016
From: TAKEDA NYCOMED AS
To: TAKEDA AS
Reel/Frame 037484/0481 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 17, 2014
From: BERTELSEN, POUL; PEDERSEN, PERNILLE DYBENDAL; LARSEN, HENRIK NEUSCHAFER
To: TAKEDA NYCOMED AS
Reel/Frame 034188/0699 →
Priority Claims (2)
DK 2012 50178 · May 24, 2012 · national
EP 12194089 · Nov 23, 2012 · regional
Continuity (1)
Related Publication 20150130112A1 · May 14, 2015