Bacterial composition for the treatment of colibacillosis on farms, in particular poultry farms, and also drinking water containing such a bacterial composition
A bacterial composition for the treatment of colibacillosis on farms, in particular poultry farms, contains at least 10 5 cfu/ml of at least one of the following four strains of Bacillus subtilis or of Bacillus licheniformis : NOL01, NOL02, NOL03 and NOL04, and at least 10 5 cfu/ml of at least one lactic acid bacterium chosen from the following lactic acid bacteria: Lactococcus lactis spp lactis 1 strain NOL11 and Pediococcus pentosaceus 2 strain NOL12.
1. A bacterial composition, comprising at least one strain of Bacillus and at least one lactic acid bacterium, wherein said Bacillus is selected from the group consisting of: NOL01, NOL02, NOL03, and NOL04, and said lactic acid bacterium is selected from the group consisting of: Lactococcus lactis spp lactis 1 strain NOL11 and Pediococcus pentosaceus 2 strain NOL12, wherein said bacterial composition comprises at least about 10 5 cfu/ml of said Bacillus and at least about 10 5 cfu/ml of said lactic acid bacteria.
2. The bacterial composition according to claim 1 , wherein said bacterial composition comprises between 10 5 and 10 9 cfu/ml of said Bacillus and between 10 9 and 10 10 cfu/ml of said lactic acid bacteria.
3. The bacterial composition according to claim 1 , wherein said composition is in sporulated form, in vegetative form, or in a mixture of both sporulated and vegetative form.
4. The bacterial composition according to claim 1 , wherein the composition comprises at least one of the compositions selected from the group consisting of:
the strain NOL 01 and the strain NOL 11;
the strain NOL 01 and the strain NOL 12;
the strain NOL 02 and the strain NOL 11;
the strain NOL 02 and the strain NOL 12;
the strain NOL 03 and the strain NOL 11;
the strain NOL 03 and the strain NOL 12;
the strain NOL 04 and the strain NOL 12; and
the strains NOL 01, NOL 02, NOL 03 and NOL 04, at a concentration from 10 5 to 10 8 cfu/ml and the strains NOL 11 and NOL12 at a concentration from 10 9 to 10 10 cfu/ml.
5. The bacterial composition according to claim 1 , wherein:
the strain NOL 01 is the strain deposited at the Institut Pasteur under the Budapest treaty under the number CNCM I-4606;
the strain NOL 03 is the strain deposited at the Institut Pasteur under the Budapest treaty under the number CNCM I-4607;
the strain NOL 04 is the strain deposited at the Institut Pasteur under the Budapest treaty under the number CNCM I-4608;
the strain NOL 11 is the strain deposited at the Institut Pasteur under the Budapest treaty under the number CNCM I-4609; and
the strain NOL 12 is the strain deposited at the Institut Pasteur under the Budapest treaty under the number CNCM I-4610.
6. A method for treating colibacillosis infections in animal farms, comprising the steps of:
administering to an animal of an effective amount of a bacterial composition, wherein said bacterial composition comprises at least 10 5 cfu/ml of at least one of the strain of Bacillus strains selected from the group consisting of: NOL01, NOL02, NOL03 and NOL04, and at least 10 5 cfu/ml of at least one lactic acid bacterium selected from the group consisting of: Lactococcus lactis spp lactis 1 strain NOL11 and Pediococcus pentosaceus 2 strain NOL12.
7. The method of claim 6 , wherein said bacterial composition comprises between 10 5 and 10 9 cfu/ml of bacillus and between 10 9 and 10 10 cfu/ml of lactic acid bacteria.
8. The method of claim 6 , wherein said bacterial composition is in sporulated form, in vegetative form, or in a mixture of sporulated and vegetative form.
9. The method of claim 6 , wherein said bacterial composition comprises at least one of the compositions selected from the group consisting of:
the strain NOL 01 and the strain NOL 11;
the strain NOL 01 and the strain NOL 12;
the strain NOL 02 and the strain NOL 11;
the strain NOL 02 and the strain NOL 12;
the strain NOL 03 and the strain NOL 11;
the strain NOL 03 and the strain NOL 12;
the strain NOL 04 and the strain NOL 12; and
the strains NOL 01, NOL 02, NOL 03 and NOL 04, at a concentration from 10 5 to 10 8 cfu/ml and the strains NOL 11 and NOL12 at a concentration from 10 9 to 10 10 cfu/ml.
10. The method of claim 6 , wherein:
the strain NOL 01 is the strain deposited at the Institut Pasteur under the Budapest treaty under the number CNCM I-4606;
the strain NOL 03 is the strain deposited at the Institut Pasteur under the Budapest treaty under the number CNCM I-4607;
the strain NOL 04 is the strain deposited at the Institut Pasteur under the Budapest treaty under the number CNCM I-4608;
the strain NOL 11 is the strain deposited at the Institut Pasteur under the Budapest treaty under the number CNCM I-4609; and
the strain NOL 12 is the strain deposited at the Institut Pasteur under the Budapest treaty under the number CNCM I-4610.
11. The method of claim 6 , wherein the animal farm is a poultry farm.
12. The method of claim 6 , further comprising the step of: adding said bacterial composition to a drinking water.
13. A drinking water for a farm animal, comprising:
an effective amount of water; and
a bacterial composition, comprising at least 10 5 cfu/ml of at least one Bacillus selected from the group consisting of: NOL01, NOL02, NOL03 and NOL04; and at least 10 5 cfu/ml of at least one lactic acid bacterium selected from the group consisting of: Lactococcus lactis spp lactis 1 strain NOL11 and Pediococcus pentosaceus 2 strain NOL12.
14. The drinking water according to claim 13 , wherein said bacterial composition comprises at least one of the compositions selected from the group consisting of:
the strain NOL 01 and the strain NOL 11;
the strain NOL 01 and the strain NOL 12;
the strain NOL 02 and the strain NOL 11;
the strain NOL 02 and the strain NOL 12;
the strain NOL 03 and the strain NOL 11;
the strain NOL 03 and the strain NOL 12;
the strain NOL 04 and the strain NOL 12; and
the strains NOL 01, NOL 02, NOL 03 and NOL 04, at a concentration from 10 5 to 10 8 cfu/ml and the strains NOL 11 and NOL12 at a concentration from 10 9 to 10 10 cfu/ml.
15. The drinking water according to claim 13 , wherein:
the strain NOL 01 is the strain deposited at the Institut Pasteur under the Budapest treaty under the number CNCM I-4606;
the strain NOL 03 is the strain deposited at the Institut Pasteur under the Budapest treaty under the number CNCM I-4607;
the strain NOL 04 is the strain deposited at the Institut Pasteur under the Budapest treaty under the number CNCM I-4608;
the strain NOL 11 is the strain deposited at the Institut Pasteur under the Budapest treaty under the number CNCM I-4609; and
the strain NOL 12 is the strain deposited at the Institut Pasteur under the Budapest treaty under the number CNCM I-4610.