IP Library › Granted Patent US 10,092,905
Granted Patent B2
US 10,092,905 · App. 14/406,899 · Granted Oct 9, 2018

Tissue sample container and methods

Inventors: Jo Fleming (Boulder, CO); Charles E. Clemens (Encinitas, CA); David Berardelli (San Diego, CA)
Assignee: Leica Biosystems Nussloch GmbH
B01L3/50853A61B10/0096B01L3/502715B01L3/545G01N1/36B01L2300/04F04C2270/041G01N2001/368
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Quick Facts
Patent No.
US 10,092,905
App. No.
14/406,899
Granted
Oct 9, 2018
Kind
B2
Abstract

A tissue sample container including a base having a plurality of sample holding sections, which are configured to receive a plurality of tissue samples in a given orientation and are demarcated by section walls; and a lid configured to sealingly engage the base. The sample holding sections are sized and shaped to correspond to a specific tissue sample size and shape such that the base in cooperation with the section walls, maintain the given orientation and identity of the tissue samples within respective sample holding sections.

Claims (31)

1. A tissue sample container, comprising:

a base having a plurality of sample holding sections which receive a plurality of tissue samples in a given orientation, said sample holding sections being demarcated by section walls;

a lid configured to sealingly engage the base, and

a fluid dispensing pouch enclosing a fluid and having a frangible portion which is in fluid communication with the inside of the tissue sample container for dispensing a fluid inside the tissue sample container while the lid and the base are engaged,

wherein the sample holding sections are sized and shaped to correspond to a specific tissue sample size and shape such that the base in cooperation with the section walls, when the sample contacts the section wall, maintains the given orientation and identity of the tissue samples within respective sample holding sections, and

wherein said pouch is disposed inside the tissue sample container and the frangible portion is configured to release the fluid into the tissue sample container in response to engaging the lid and the base.

2. The tissue sample container according to claim 1 , wherein tissue samples are core biopsy samples at the sample holding sections are shaped and sized to maintain the orientation of core biopsy samples.

3. The tissue sample container according to claim 1 , wherein the plurality of sample holding sections are each configured to receive one of the pluralities of tissue samples.

4. The tissue sample container according to claim 1 , wherein said sample holding sections are in fluid communication with each other.

5. The tissue sample container according to claim 1 , wherein said sample holding sections are not in fluid communication with each other.

6. The tissue sample container according to claim 1 , wherein the fluid is a fixing agent chemical selected to fix and preserve the tissue samples for analysis.

7. The tissue sample container according to claim 1 , wherein said fluid dispensing mechanism is a porthole on the outside of the lid configured to receive said fluid.

8. The tissue sample container according to claim 1 , wherein said pouch is disposed in the lid.

9. The tissue sample container according to claim 1 , further comprising a label attached to at least one of the lid or the base.

10. The tissue sample container according to claim 9 , wherein the label is a computer readable label.

11. The tissue sample container according to claim 10 , wherein the computer readable label comprises at least one of a readable writable RFID, a one-dimensional barcode, a two-dimensional barcode and a three-dimensional barcode.

12. The tissue sample container according to claim 11 , wherein the computer readable label contains unique information to at least one of the tissue sample container and one of the plurality of tissue samples.

13. The tissue sample container according to claim 12 , wherein the unique information includes one or more of patient identification information, sample collection site location information, collection temperature, collection time, and collection conditions.

14. The tissue sample container according to claim 1 , further comprising an identifier to identify the tissue samples within the tissue container.

15. The tissue sample container according to claim 1 , further comprising an identifier to identify the proper orientation of the tissue container.

16. The tissue sample container according to claim 1 ,

wherein the lid is a substantially cylindrically shaped lid configured to screwingly seal and engage the base.

17. The tissue sample container according to claim 1 , further comprising a seal gasket between the base and the lid.

18. The tissue sample container according to claim 1 , wherein the lid further comprises a first snap and a second snap configured to respectively engage with a first lock and a second lock on the base to secure the base and lid member.

19. The tissue sample container according to claim 1 , the lid comprises a film member.

20. The tissue sample container according to claim 19 , wherein the film member is heat scalable.

21. The tissue sample container according to claim 20 , wherein the film is attached to the base in a heat scalable manner.

22. The tissue container according to claim 1 , wherein the section walls contain perforations to define the plurality of sample holding sections and allow the sample holding sections to be in fluid communication with each other.

23. The tissue sample container according to claim 1 , wherein the section walls prevent the plurality of tissue samples from passing between respective sample holding sections.

24. The tissue sample container according to claim 1 ,

wherein the sample holding sections are differently sized and shaped to correspond to respective differently sized and shaped tissue samples.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 29, 2018
From: FLEMING, JO; CLEMENS, CHARLES; BERARDELLI, DAVID
To: LEICA BIOSYSTEMS NUSSLOCH GMBH
Reel/Frame 044752/0395 →
Continuity (3)
Provisional Application 61663326 · Jun 22, 2012
Provisional Application 61792929 · Mar 15, 2013
Related Publication 20150158027A1 · Jun 11, 2015