Aqueous composition for preparing hard capsule, preparation method therefor, hard capsule, and method for recycling hard capsule scraps
Disclosed are an aqueous composition for preparing a hard capsule, a preparation method therefor, a hard capsule, and a method for recycling hard capsule scraps. The disclosed aqueous composition for preparing a hard capsule comprises a water-soluble cellulose ether, an alcohol, and water. In addition, the method for recycling hard capsule scraps comprises the step of dissolving hard capsule scraps comprising a water-soluble cellulose ether into a mixture solution comprising water and an alcohol so as to prepare an aqueous composition for preparing a recycled hard capsule.
1. An aqueous composition for preparing a hard capsule, the aqueous composition comprising a cellulose ether solution, the cellulose ether solution comprising:
a water-soluble cellulose ether;
an alcohol; and
water,
wherein non-dissolved materials are absent from the aqueous composition,
wherein the aqueous composition comprises 10 to 25 wt % of the water-soluble cellulose ether, 5 to 30 wt % of the alcohol and 0.05 to 5.0 wt % of a gelation agent; wherein the alcohol comprises ethanol, methanol, isopropanol, butanol, or a mixture of two or more of these; wherein the water-soluble cellulose ether comprises hydroxypropyl methylcellulose(HPMC), hydroxyethyl methylcellulose(HEMC), methylcellulose(MC), or a mixture of two or more of these.
2. The aqueous composition of claim 1 , wherein the gelation agent is selected from Carrageenan, Gellan gum, Xanthan gum, Pectin, and a mixture of two or more of these.
3. The aqueous composition of claim 1 , wherein the aqueous composition further comprises more than 0 wt % and up to 1.0 wt % of a gelation aid selected from potassium chloride, potassium acetate, calcium chloride, and a mixture of two or more of these.
4. A method of preparing an aqueous composition for preparing a hard capsule, the method comprising preparing a cellulose ether solution that contains water, an alcohol and a water-soluble cellulose ether, and that is maintained in a range of 40 to 70° C. higher than an atmospheric temperature, and adding a gelation agent to the cellulose ether solution; wherein the alcohol comprises ethanol, methanol, isopropanol, butanol, or a mixture of two or more of these,
wherein non-dissolved materials are absent from the aqueous composition,
wherein the aqueous composition comprises 10 to 25 wt % of the water-soluble cellulose ether, 0.05 to 5.0 wt % of a gelation agent, and 5 to 30 wt % of the alcohol; wherein the water-soluble cellulose ether comprises hydroxypropyl methylcellulose(HPMC), hydroxyethyl methylcellulose(HEMC), methylcellulose(MC), or a mixture of two or more of these.
5. A hard capsule prepared by using the aqueous composition of claim 1 .
6. A method of recycling a hard capsule scrap, the method comprising preparing an aqueous composition for preparing a recycled hard capsule by dissolving the hard capsule scrap containing water-soluble cellulose ether in a mixed solution including water and an alcohol,
wherein non-dissolved materials are absent from the aqueous composition,
wherein the aqueous composition comprises 10 to 25 wt % of the water-soluble cellulose ether, 5 to 30 wt % of the alcohol and 0.05 to 5.0 wt % of a gelation agent; wherein the alcohol comprises ethanol, methanol, isopropanol, butanol, or a mixture of two or more of these, wherein the temperature of the aqueous composition is in a range of 40 to 70° C.; wherein the water-soluble cellulose ether comprises hydroxypropyl methylcellulose(HPMC), hydroxyethyl methylcellulose(HEMC), methylcellulose(MC), or a mixture of two or more of these.
7. The method of claim 6 , wherein
the hard capsule scrap includes 90 to 95 parts by weight of the water-soluble cellulose ether, 0.05 to 5.0 parts by weight of a gelation agent, 0 to 1.0 parts by weight of a gelation aid, and 1.0 to 7.0 parts by weight of water.
8. The method of claim 6 , wherein
the step of preparing the aqueous composition for preparing a recycled hard capsule comprises dissolving additional water-soluble cellulose ether together with the hard capsule scrap in a mixed solution including water and an alcohol.
9. The method of claim 6 or 8 , further comprising
maintaining the aqueous composition for preparing a recycled hard capsule at a temperature of 40 to 70° C. for 2 to 12 hours.
10. The method of claim 9 , further comprising
adding at least one of an additional gelation agent and an additional gelation aid to the aqueous composition for preparing a recycled hard capsule.
11. The method of claim 9 , further comprising
coating the aqueous composition for preparing a recycled hard capsule on a substrate and drying the aqueous composition.
12. The method of claim 6 , wherein the aqueous composition for preparing a recycled hard capsule further comprises
more than 0 wt % and up to 1.0 wt % of the gelation aid.