Immunoparticles and methods of generating and using same
A pharmaceutical composition comprising an immunoparticle is provided. The pharmaceutical composition comprising a monoclonal secondary antibody immunocomplexed with a primary antibody, wherein said monoclonal secondary antibody is coupled on an outer surface of a particle and wherein said particle is loaded with a pharmaceutical agent.
1. An immunoparticle comprising a humanized secondary antibody coupled on an outer surface of a particle, wherein said secondary antibody is bound specifically to an Fc region of an isolated humanized or human primary antibody.
2. The immunoparticle of claim 1 , wherein said immunoparticle is loaded with a pharmaceutical agent.
3. A pharmaceutical composition comprising the immunoparticle of claim 1 .
4. A universal kit for in-vivo delivery of a pharmaceutical agent, the kit comprising the immunoparticle of claim 2 .
5. The immunoparticle of claim 1 , wherein said isolated humanized secondary antibody is an IgG1.
6. The immunoparticle of claim 1 , wherein said isolated humanized secondary antibody binds an IgG humanized or human primary antibody.
7. The immunoparticle of claim 1 , wherein said isolated humanized or human primary antibody is IgG.